Cannabidiol Use for Fibromyalgia: Prevalence of Use and Perceptions of Effectiveness in a Large Online Survey.

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Cannabidiol (CBD) is widely advertised as helpful for chronic pain management but research is limited. Using a cross-sectional, anonymous survey, we examined patterns of naturalistic CBD use among individuals with […]

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Altered regulation of negative affect in patients with fibromyalgia: A diary study.

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Fibromyalgia is characterized by widespread musculoskeletal pain and often accompanied by cognitive and emotional problems. Adaptation to fibromyalgia may therefore also rely on one’s ability to regulate emotional problems. In […]

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III. Detecting Treatment Effects in Clinical Trials With Different Indices of Pain Intensity Derived From Ecological Momentary Assessment.

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Pain intensity represents the primary outcome in most pain clinical trials. Identifying methods to measure aspects of pain that are most sensitive to treatment may facilitate discovery of effective interventions. […]

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Clinical, psychological and quality of life differences in fibromyalgia patients from secondary and tertiary healthcare.

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The “funnel effect” of Fibromyalgia (FM) assumes that as patients access healthcare services, they present greater severity and a more complex clinical situation than individuals with FM from the general […]

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A retrospective observational study comparing somatosensory amplification in fibromyalgia, chronic pain, psychiatric disorders and healthy subjects.

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Objectives Somatosensory amplification (SA) has been described as an important feature of somatoform disorders, and an “amplifying somatic style” has been reported as a negative connotation of body perception. As […]

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Brief Acceptance and Commitment Therapy for Fibromyalgia: Feasibility and Effectiveness of a Replicated Single-Case Design.

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Overall, the literature on the effectiveness of psychological treatments in general and those for fibromyalgia in particular has been dominated by research designs that focus on large groups and explore […]

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Effects of Workplace-Related Factors on the Prevalence of Fibromyalgia among Israeli Kindergarten Teachers.

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Fibromyalgia syndrome (FMS), a chronic widespread pain disorder, has been associated with various models of stress, including those that are workplace-related. In a previous study, we have documented the significantly […]

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Time course of DNA methylation in pain conditions: from experimental models to humans.

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Throughout the last decade, research has uncovered associations between pain and epigenetic alterations caused by environmental factors. Specifically, studies have demonstrated correlations between pain conditions and altered DNA methylation patterns. […]

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Polymorphisms of the μ-opioid receptor gene influence cerebral pain processing in fibromyalgia.

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Dysregulation of the μ-opioid receptor has been reported in fibromyalgia (FM) and was linked to pain severity. Here we investigated the effect of the functional genetic polymorphism of the μ-opioid […]

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Metabolomics in Chronic Pain Research.

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Metabolomics deals with the identification and quantification of small molecules (metabolites) in biological samples. As metabolite levels can reflect normal or altered metabolic pathways, their measurement provides information to improve […]

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Exploring the contextual role of pain severity as a moderator of the relationship between activity patterns and the physical and mental functioning of women with fibromyalgia.

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In past years, and mostly due to contextual psychological therapies, it has been argued that particular behavioral patterns may be useful in certain contexts, but not in others. The goal […]

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Overlap of Five Chronic Pain Conditions: Temporomandibular Disorders, Headache, Back Pain, Irritable Bowel Syndrome, and Fibromyalgia.

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To assess cohort retention in the OPPERA project and to compare the degree of overlap between pairs of chronic overlapping pain conditions (COPCs) using a cross-sectional analysis of data from […]

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Clinical Characteristics of Pain Among Five Chronic Overlapping Pain Conditions.

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To describe the pain characteristics of five index chronic overlapping pain conditions (COPCs) and to assess each COPC separately in order to determine whether the presence of comorbid COPCs is […]

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Experimental Pain Sensitivity in Subjects with Temporomandibular Disorders and Multiple Other Chronic Pain Conditions: The OPPERA Prospective Cohort Study.

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To investigate associations between experimental pain sensitivity and five chronic pain conditions among 655 participants in the OPPERA study.Quantitative sensory tests were used to measure sensitivity to three modalities of […]

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Attributes Germane to Temporomandibular Disorders and Their Associations with Five Chronic Overlapping Pain Conditions.

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To investigate whether TMD-related characteristics are indeed specific to TMD or whether they are also associated with other chronic overlapping pain conditions (COPCs).In this cross-sectional study, 22 characteristics related broadly […]

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Associations of Sleep Disturbance, Atopy, and Other Health Measures with Chronic Overlapping Pain Conditions.

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To quantify the contributions of atopic disorders, sleep disturbance, and other health conditions to five common pain conditions.This cross-sectional analysis used data from 655 participants in the OPPERA study. The […]

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Associations of Psychologic Factors with Multiple Chronic Overlapping Pain Conditions.

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To characterize psychologic functioning across five chronic overlapping pain conditions (COPCs)-temporomandibular disorders, fibromyalgia, low back pain, headache, and irritable bowel syndrome-and their overlaps.Participants were 655 adults in the OPPERA study. […]

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Prescription of exercises for the treatment of chronic pain along the continuum of nociplastic pain: a systematic review with meta-analysis.

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To compare different exercise prescriptions for patients with chronic pain along the continuum of nociplastic pain: fibromyalgia, chronic whiplash-associated disorders (CWAD), and chronic idiopathic neck pain (CINP).Randomized controlled trials comparing […]

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Perceived validation and criticism in pain: development of a new measure in chronic pain.

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Research suggests that the way others react to a pain flare-up impacts on psychological and pain-related symptoms in chronic pain (CP). Experiencing validation from others is associated with less negative […]

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Sifting the wheat from the chaff? Evidence for the existence of an asymmetric fibromyalgia phenotype.

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The different phenotypic presentations of fibromyalgia (FM) have been infrequently studied and may have diagnostic and therapeutic implications. The aim of this study was to explore differences between FM patients […]

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Factors associated with participation and nonparticipation in a VA Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP).

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As part of the evaluation of the Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP), we compared demographic and health characteristics between participants and nonparticipants drawn from […]

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Comorbidities of self-reported fibromyalgia in United States adults: A cross-sectional study from The National Epidemiological Survey on Alcohol and Related Conditions (NESARC-III).

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Fibromyalgia has been associated with various physical and mental disorders. However, these comorbidities need to be quantified in a population-based study.We compared participants with and without self-reported fibromyalgia to assess […]

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Convergent and Discriminant Validity of the Serbian Version of the Central Sensitization Inventory.

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The goal of the present study was to explore additional evidence of validity of the Serbian version of the Central Sensitization Inventory (CSI), a patient-reported outcome measure of symptoms that […]

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Treatment preferences in fibromyalgia patients: A cross-sectional web-based survey.

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Therapeutic approaches to fibromyalgia (FM) are shifting towards a combined multi-treatment approach to tackle the variety of symptoms experienced in FM. Importantly, little is known about FM patients’ attitude towards […]

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