The aim of this study was to use human genetics to investigate the pathogenesis of sick sinus syndrome (SSS) and the role of risk factors in its development.We performed a […]» Read more
Ischaemic stroke is a severe complication of rheumatic heart disease (RHD), which may result in permanent disability and death. This study aimed to assess the incidence and predictors of stroke […]» Read more
Usefulness of Post -Procedural Plasma Brain Natriuretic Peptide Levels to Predict Recurrence After Catheter Ablation of Atrial Fibrillation in Patients with Left Ventricular Systolic Dysfunction.
Catheter ablation (CA) of atrial fibrillation (AF) improves cardiac function, resulting in a decrease in plasma brain natriuretic peptide (BNP) levels in patients with reduced left ventricular ejection fraction (LVEF). […]» Read more
Prevalence and Determinants of Atrial Fibrillation-associated In-hospital Ischemic Stroke in patients with Acute Myocardial Infarction undergoing Percutaneous Coronary Intervention.
Atrial Fibrillation (AF) is an established risk factor ischemic stroke (IS) and is commonly encountered in patient hospitalized with acute myocardial infarction (AMI). Uncommonly, IS can occur as a complication […]» Read more
Direct Oral Anticoagulants (DOACs) require dose adjustment based on specific patient characteristics, making them prone to incorrect dosing. The current study aimed to evaluate the prevalence of inappropriate DOAC dosing, […]» Read more
Impact of Baseline Right Bundle Branch Block on Outcomes after Pulmonary Vein Isolation in Patients with Atrial Fibrillation.
Right bundle branch block (RBBB) is one of the most frequent alterations of the electrocardiogram. Several studies have shown that RBBB is a risk factor of cardiovascular diseases. However, the […]» Read more
Influence of Chronic Obstructive Pulmonary Disease on Atrial Mechanics by Speckle Tracking Echocardiography in Patients with Atrial Fibrillation.
The present study aimed to examine differences in left- and right atrial characteristics between atrial fibrillation (AF) patients with and without chronic obstructive pulmonary disease (COPD). For this, 420 patients […]» Read more
Relation of Left Atrial Enlargement to Subsequent Thromboembolic Events in Non-Valvular Atrial Fibrillation Patients with Low to Borderline Embolic Risk.
The current thromboembolic risk stratification of non-valvular atrial fibrillation (NVAF) does not include parameters from transthoracic echocardiography (TTE). We hypothesized that left atrial enlargement (LAE) on TTE could discriminate who […]» Read more
Prognostic Value of Pre-operative Atrial Fibrillation in Patients with Secondary Mitral Regurgitation Undergoing MitraClip Implantation.
Limited data are available regarding the independent prognostic role of pre-operative AF after transcatheter mitral valve repair with MitraClip. We sought to evaluate the impact of pre-operative atrial fibrillation (AF) […]» Read more
Cardiac involvement in amyloidosis is associated with a poor prognosis. Data on the burden of arrhythmias in patients with cardiac amyloidosis (CA) during hospitalization is lacking. We identified the burden […]» Read more
To evaluate associations between oral anticoagulant (OAC) discontinuation and risk of ischaemic stroke (IS) among patients with atrial fibrillation (AF).We undertook a population-based cohort study with nested case-control analysis using […]» Read more
Meta-Analysis Evaluating the Efficacy and Safety of Low-Intensity Warfarin for Patients >65 Years of Age with Non-Valvular Atrial Fibrillation.
Non-valvular atrial fibrillation(NVAF) is the most common arrhythmia. It is of a high disability and death rate, and seriously affects quality of life. Although NOACs are recommended for anticoagulation therapy […]» Read more
Meta-Analysis of the Usefulness of Catheter Ablation of Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction.
Catheter ablation improves clinical outcomes in atrial fibrillation (AF) patients with heart failure (HF) with reduced ejection fraction (HFrEF). However, the role of catheter ablation in HF with a preserved […]» Read more
Periprocedural Stroke After Coronary Revascularization (From the CREDO-Kyoto PCI/CABG Registry Cohort-3).
There is a scarcity of data on incidence, risk factors, especially clinical severity, and long-term prognostic impact of periprocedural stroke after coronary revascularization in contemporary real-world practice. Among 14867 consecutive […]» Read more
Bleeding risk with rivaroxaban compared with vitamin K antagonists in patients aged 80 years or older with atrial fibrillation.
Direct oral anticoagulants have been evaluated in the general population, but proper evidence for their safe use in the geriatric population is still missing. We compared the bleeding risk of […]» Read more
Natriuretic peptides are an important prognostic marker in patients with heart failure (HF). However, little is known regarding their prognostic significance in patients with atrial fibrillation (AF) without HF and […]» Read more
Relation of Atrial Fibrillation to Angiographic Characteristics and Coronary Artery Disease Severity in Patients Undergoing Percutaneous Coronary Intervention.
Patients with atrial fibrillation (AF) have an increased risk of coronary artery disease (CAD) compared to patients without. Angiographic characteristics, clinical presentation and severity of CAD according to the presence […]» Read more
Various predictors of atrial fibrillation (AF) recurrence have been shown based on the baseline characteristics before catheter ablation (CA). This study aimed to develop a novel scoring system for predicting […]» Read more
Chronic obstructive pulmonary disease (COPD) is highly prevalent among patients with atrial fibrillation (AF), shares common risk factors, and adds to the overall morbidity and mortality in this population. Additionally, […]» Read more
The term athlete’s heart describes structural, functional and electrical adaptations of the cardiovascular system due to repetitive intense exercise. Physiological cardiac adaptations in athletes, however, may mimic features of cardiac […]» Read more
The effects of rivaroxaban in patients with atrial fibrillation and a bioprosthetic mitral valve remain uncertain.In this randomized trial, we compared rivaroxaban (20 mg once daily) with dose-adjusted warfarin (target […]» Read more
Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in maintaining sinus […]» Read more
Meta-Analysis of Safety and Efficacy of Direct Oral Anticoagulants Versus Warfarin According to Time in Therapeutic Range in Atrial Fibrillation.
Among atrial fibrillation (AF) patients, it is unclear whether the efficacy and safety of direct oral anticoagulants (DOAC) relative to warfarin is consistent across various levels of international normalized ratio […]» Read more
Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences.
The dilated cardiomyopathy (DCM) phenotype is the result of combined genetic and acquired triggers. Until now, clinical decision-making in DCM has mainly been based on ejection fraction (EF) and NYHA […]» Read more
Cardiac Computed Tomography-Derived Left Atrial Volume Index as a Predictor of Long-Term Success of Cryo-Ablation in Patients with Atrial Fibrillation.
Patients with symptomatic, drug-refractory atrial fibrillation (AF) are frequently treated with catheter ablation. Cryo-ablation has been established as an alternative to radiofrequency ablation but long-term outcome data are still limited. […]» Read more
This study aimed to estimate the global burden of atrial fibrillation/atrial flutter (AF/AFL).We retrieved data from the Global Health Data Exchange query tool and estimated the age-standardised rates (ASRs) of […]» Read more
Incidental Thoracic Aortic Dilation On Chest Computed Tomography In Patients With Atrial Fibrillation.
Individuals with atrial fibrillation (AF) have risk factors that predispose to thoracic aneurysmal disease (TAD) and atherosclerosis. In this study in individuals with AF, we assessed the occurrence of incidental […]» Read more
“Pill In The Pocket” Antiarrhythmic Drugs For Orally Administered Pharmacologic Cardioversion Of Atrial Fibrillation.
The therapy of atrial fibrillation (AF) often involves the use of a rhythm control strategy, in which one or more antiarrhythmic drugs (AAD), ablative procedures, and/or hybrid approaches involving both […]» Read more
To explore the association between three-dimensional (3D) cardiac magnetic resonance (CMR) feature tracking (FT) right ventricular peak global longitudinal strain (RVpGLS) and major adverse cardiovascular events (MACEs) in patients with […]» Read more
To assess temporal clinical and budget impacts of changes in atrial fibrillation (AF)-related prescribing in England.Data on AF prevalence, AF-related stroke incidence and prescribing for all National Health Service general […]» Read more