Systolic Blood Pressure and Risk for Ventricular Arrhythmia in Patients with an Implantable Cardioverter Defibrillator.

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Low systolic blood pressure (SBP) was previously suggested to be a marker for heart failure and mortality in patients with low left ventricular (LV) ejection fraction (EF). We aimed to […]

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Impact of Arrhythmias on Hospitalizations in Patients with Cardiac Amyloidosis.

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Cardiac involvement in amyloidosis is associated with a poor prognosis. Data on the burden of arrhythmias in patients with cardiac amyloidosis (CA) during hospitalization is lacking. We identified the burden […]

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Prognostic value of automated longitudinal strain measurements in asymptomatic aortic stenosis.

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Two-dimensional (2D) longitudinal strain (LS) predicts cardiac events in aortic stenosis (AS). However, it requires manual editing, which affects its accuracy and reliability. We investigated whether left ventricular (LV), left […]

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Meta-Analysis Evaluating the Efficacy and Safety of Low-Intensity Warfarin for Patients >65 Years of Age with Non-Valvular Atrial Fibrillation.

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Non-valvular atrial fibrillation(NVAF) is the most common arrhythmia. It is of a high disability and death rate, and seriously affects quality of life. Although NOACs are recommended for anticoagulation therapy […]

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Translational applications of computational modelling for patients with cardiac arrhythmias.

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Cardiac arrhythmia is associated with high morbidity, and its underlying mechanisms are poorly understood. Computational modelling and simulation approaches have the potential to improve standard-of-care therapy for these disorders, offering […]

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The risk of cardiac events in patients receiving immune checkpoint inhibitors: a nationwide Danish study.

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The study aimed to estimate the risk of cardiac events in immune checkpoint inhibitor (ICI)-treated patients with lung cancer or malignant melanoma.The study included consecutive patients with lung cancer or […]

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Risk of Hypertrophic Cardiomyopathy with Contemporary Management Strategies Implemented In Non-Referral Regional Community-Based Practices.

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Major advances in diagnosis and treatment have emerged for hypertrophic cardiomyopathy (HCM), largely in major tertiary referral centers dedicated to this disease. Whether these therapeutic benefits are confined to patients […]

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Does night-time aircraft noise trigger mortality? A case-crossover study on 24 886 cardiovascular deaths.

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It is unclear whether night-time noise events, including from aeroplanes, could trigger a cardiovascular death. In this study, we investigate the potential acute effects of aircraft noise on mortality and […]

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Arrhythmias right ventricular cardiomyopathy and sports activity: from molecular pathways in diseased hearts to new insights into the athletic heart mimicry.

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Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited disease associated with a high risk of sudden cardiac death. Among other factors, physical exercise has been clearly identified as a strong […]

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Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation.

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Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in maintaining sinus […]

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Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure.

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The selective cardiac myosin activator omecamtiv mecarbil has been shown to improve cardiac function in patients with heart failure with a reduced ejection fraction. Its effect on cardiovascular outcomes is […]

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Endocrine therapy use and cardiovascular risk in postmenopausal breast cancer survivors.

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Examine the effect of tamoxifen and aromatase inhibitors (AIs) on the risk of 12 clinically relevant cardiovascular outcomes in postmenopausal female breast cancer survivors.We carried out two prospective cohort studies […]

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Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences.

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The dilated cardiomyopathy (DCM) phenotype is the result of combined genetic and acquired triggers. Until now, clinical decision-making in DCM has mainly been based on ejection fraction (EF) and NYHA […]

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Peripheral venous pressure changes during exercise are associated with adverse Fontan outcomes.

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Elevated central venous pressure (CVP) plays an important role in the development of adverse Fontan outcomes. Peripheral venous pressure (PVP) has been validated as a surrogate for CVP in Fontan […]

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Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ≥ 65 Years of Age with a Low Ejection Fraction Following Coronary Revascularization.

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The purpose of this analysis was to assess implantable cardioverter-defibrillator (ICD) utilization and its association with mortality among patients ≥ 65 years of age following coronary revascularization. Patients in the […]

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Previously Undetected Obstructive Sleep Apnea in Patients with New-Onset Atrial Fibrillation.

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Obstructive sleep apnea-hypopnea syndrome (OSA) compromises the efficacy of atrial fibrillation (AF) control strategies. Continuous positive airway pressure (CPAP) may ameliorate arrhythmia control especially in early AF stages (new-onset AF). […]

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Changes in quality of life, cognition and functional status following catheter ablation of atrial fibrillation.

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To investigate changes in quality of life (QoL), cognition and functional status according to arrhythmia recurrence after atrial fibrillation (AF) ablation.We compared QoL, cognition and functional status in patients with […]

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Trends in Costs and Risk Factors of 30-Day Readmissions for Transcatheter Aortic Valve Implantation.

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As transcatheter aortic valve implantation (TAVI) continues its rapid growth as a treatment approach for aortic stenosis, costs associated with TAVI and its burden to healthcare systems will assume greater […]

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Utility of Cardiac Magnetic Resonance Imaging Versus Cardiac Positron Emission Tomography for Risk Stratification for Ventricular Arrhythmias in Patients With Cardiac Sarcoidosis.

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Abnormalities on cardiac magnetic resonance imaging (CMR) and positron emission tomography (PET) predict ventricular arrhythmias (VA) in patients with cardiac sarcoidosis (CS). Little is known whether concurrent abnormalities on CMR […]

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Comparison of Outcomes in Patients with Takotsubo Syndrome with-vs-without Cardiogenic Shock.

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There is limited data on the in-hospital outcomes of cardiogenic shock (CS) secondary to takotsubo syndrome (TS). We aimed to assess the incidence, predictors and outcomes of CS in hospitalized […]

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Comparison of Outcomes After Ablation of Atrial Fibrillation in Patients With Heart Failure with Preserved Versus Reduced Ejection Fraction.

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Catheter ablation improves outcomes in atrial fibrillation (AF) patients with heart failure (HF) with reduced ejection fraction (HFrEF). We sought to evaluate the efficacy and safety of catheter ablation of […]

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Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices.

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We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients […]

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