HIV viral load trends during the COVID-19 pandemic in a reference center for HIV in Rome, Italy.

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COVID-19 pandemic has reduced the access of HIV patients to reference centers. However, retention-in-care is critical to maintain adherence to therapy and viral suppression. During lockdown in Italy, our center […]

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The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.

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This review provides an update on recently published literature on the rise of illicit fentanyls, risks for overdose, combinations with other substances, e.g. stimulants, consequences, and treatment.Overdose due to illicit […]

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Thoughts on “AIDS and COVID-19: A Tale of Two Pandemics and the Role of Statisticians” by Susan S. Ellenberg and Jeffrey S. Morris.

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Human immunodeficiency virus and Covid-19 (or SARS-CoV-2) differ in their incubation distributions and in their susceptibility to immunologic defense. These features affect our ability to predict the course of these […]

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Prejudicial beliefs and COVID-19 disruptions among sexual minority men living with and not living with HIV in a high SARS-CoV-2 prevalence area.

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The COVID-19 pandemic has had profound health and social impacts. COVID-19 also affords opportunities to study the emergence of prejudice as a factor in taking protective actions. This study investigated […]

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Are Individuals with Substance Use Disorders at Higher Risk of SARS-CoV-2 Infection? Population-Based Registry Study in Northern Italy.

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This study assesses whether individuals with substance use disorder are at greater risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than people in the general population.A population-based study […]

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Care, crisis and coalition: imagining antiprophylactic citizenship through AIDS hospice activism.

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Using crip theory, specifically Barounis’ formulation of antiprophylactic citizenship, Piepzna-Samarasinha’s conceptualisation of care work, and Shotwell’s calls against purity, this paper analyses the making of the film HIV in the […]

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Dolutegravir Plus Lamivudine Two-Drug Regimen: Safety, Efficacy and Diagnostic Considerations for Its Use in Real-Life Clinical Practice-A Refined Approach in the COVID-19 Era.

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The diagnostic and therapeutic management of the Coronavirus Disease 2019 (COVID-19) pandemic in the HIV population brought some known criticalities (and opportunities) to the forefront, for both those who are […]

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Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant.

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The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants threatens progress toward control of the coronavirus disease 2019 (Covid-19) pandemic. In a phase 1-2 trial involving healthy adults, […]

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Inhibitory effect of anti-HIV compounds extracted from Indian medicinal plants to retard the replication and transcription process of SARS-CoV-2: an insight from molecular docking and MD-simulation studies.

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Outbreak of Coronavirus (SARS-CoV-2) has thrown a big challenge to the globe by snatching millions of human lives from the world. In this study, inhibitory efficiency of ten anti-HIV compounds […]

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Knowledge and Impact of COVID-19 on Middle-Aged and Older People living with HIV in Lima, Peru.

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COVID-19 has had an unprecedented worldwide impact, and Peru has had one of the highest COVID-19 case rates despite implementation of an early strict nationwide quarantine. Repercussions on Peru’s healthcare […]

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Machine Learning in Discovery of New Antivirals and Optimization of Viral Infections Therapy.

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Nowadays, computational approaches play an important role in the design of new drug-like compounds and optimization of pharmacotherapeutic treatment of diseases. The emerging growth of viral infections, including those caused […]

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The Non-Specific Antiviral Activity of Polysulfates to Fight SARS-CoV-2, its Mutants and Viruses with Cationic Spikes.

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Polyanions are negatively charged macromolecules known for several decades as inhibitors of many viruses in vitro, notably AIDS virus. In the case of enveloped viruses, this activity was assigned to […]

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Prevalence and Mortality due to COVID-19 in HIV Co-Infected Population: A Systematic Review and Meta-Analysis.

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The coronavirus disease 2019 (COVID-19) was defined as a species of beta coronavirus causing atypical respiratory disease in humans. The COVID-19 pandemic has resulted in an unprecedented health and economic […]

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Adverse Psychological Reactions and Psychological Aids for Medical Staff During the COVID-19 Outbreak in China.

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Background: The outbreak of the novel coronavirus disease COVID-19 caused panic and psychological stress throughout the World. We investigated the extent of adverse psychological reactions in two medical staff groups […]

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Human immunodeficiency virus and mortality from coronavirus disease 2019: A systematic review and meta-analysis.

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Persons living with human immunodeficiency virus (PLWH) constitute a vulnerable population in view of their impaired immune status. At this time, the full interaction between HIV and severe acute respiratory […]

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Evolution of SARS-CoV-2 neutralizing antibody in an HIV-positive patient with COVID-19.

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We presented the clinical course and immune responses of a well-controlled HIV-positive patient with COVID-19. The clinical presentation and antibody production to SARS-CoV-2 were similar to other COVID-19 patients without […]

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Biomedical applications of environmental friendly poly-hydroxyalkanoates.

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Biological polyesters of hydroxyacids are known as polyhydroxyalkanoates (PHA). They have proved to be an alternative, environmentally friendly and attractive candidate for the replacement of petroleum-based plastics in many applications. […]

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Cyanobacteria-From the Oceans to the Potential Biotechnological and Biomedical Applications.

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Cyanobacteria are photosynthetic prokaryotic organisms which represent a significant source of novel, bioactive, secondary metabolites, and they are also considered an abundant source of bioactive compounds/drugs, such as dolastatin, cryptophycin […]

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Fall 2020 COVID-19 Needs Assessment among New Jersey Secondary School Educational Professionals.

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Secondary or high school (HS) educational professionals expressed concerns about dealing with environmental and occupational health and safety protocols due to COVID-19. Concerns related to fall 2020 school re-opening and […]

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Follow-Up Survey of the Impact of COVID-19 on People Living with HIV during the Second Semester of the Pandemic.

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COVID-19 affects persons living with HIV (PLWH) both directly (via morbidity/mortality) and indirectly (via disruption of HIV care). From July-November 2020, an online survey was conducted to investigate the psychosocial […]

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Phytochemicals from Plant Foods as Potential Source of Antiviral Agents: An Overview.

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To date, the leading causes of mortality and morbidity worldwide include viral infections, such as Ebola, influenza virus, acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) and recently COVID-19 […]

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Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 and Human β-Coronavirus Infection.

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Hexameric structure formation through packing of three C-terminal helices and an N-terminal trimeric coiled-coil core has been proposed as a general mechanism of class I enveloped virus entry. In this […]

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A novel pseudovirus-based mouse model of SARS-CoV-2 infection to test COVID-19 interventions.

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The spread of SARS-CoV-2, the virus that causes Coronavirus Disease 2019 (COVID-19), has been characterized as a worldwide pandemic. Currently, there are few preclinical animal models that suitably represent infection, […]

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