The active human immunodeficiency virus reservoir during antiretroviral therapy: emerging players in viral persistence.

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To discuss the role of CD4+ T cells with active Human immunodeficiency virus (HIV), meaning infected cells with transcriptional and/or translational viral activity during antiretroviral therapy (ART), focusing on new […]

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HIV viral load trends during the COVID-19 pandemic in a reference center for HIV in Rome, Italy.

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COVID-19 pandemic has reduced the access of HIV patients to reference centers. However, retention-in-care is critical to maintain adherence to therapy and viral suppression. During lockdown in Italy, our center […]

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The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.

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This review provides an update on recently published literature on the rise of illicit fentanyls, risks for overdose, combinations with other substances, e.g. stimulants, consequences, and treatment.Overdose due to illicit […]

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Thoughts on “AIDS and COVID-19: A Tale of Two Pandemics and the Role of Statisticians” by Susan S. Ellenberg and Jeffrey S. Morris.

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Human immunodeficiency virus and Covid-19 (or SARS-CoV-2) differ in their incubation distributions and in their susceptibility to immunologic defense. These features affect our ability to predict the course of these […]

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Prejudicial beliefs and COVID-19 disruptions among sexual minority men living with and not living with HIV in a high SARS-CoV-2 prevalence area.

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The COVID-19 pandemic has had profound health and social impacts. COVID-19 also affords opportunities to study the emergence of prejudice as a factor in taking protective actions. This study investigated […]

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Inhibitory effect of anti-HIV compounds extracted from Indian medicinal plants to retard the replication and transcription process of SARS-CoV-2: an insight from molecular docking and MD-simulation studies.

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Outbreak of Coronavirus (SARS-CoV-2) has thrown a big challenge to the globe by snatching millions of human lives from the world. In this study, inhibitory efficiency of ten anti-HIV compounds […]

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Knowledge and Impact of COVID-19 on Middle-Aged and Older People living with HIV in Lima, Peru.

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COVID-19 has had an unprecedented worldwide impact, and Peru has had one of the highest COVID-19 case rates despite implementation of an early strict nationwide quarantine. Repercussions on Peru’s healthcare […]

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Machine Learning in Discovery of New Antivirals and Optimization of Viral Infections Therapy.

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Nowadays, computational approaches play an important role in the design of new drug-like compounds and optimization of pharmacotherapeutic treatment of diseases. The emerging growth of viral infections, including those caused […]

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The Non-Specific Antiviral Activity of Polysulfates to Fight SARS-CoV-2, its Mutants and Viruses with Cationic Spikes.

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Polyanions are negatively charged macromolecules known for several decades as inhibitors of many viruses in vitro, notably AIDS virus. In the case of enveloped viruses, this activity was assigned to […]

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Arterial structure and function in Africans with HIV for > 5 years: longitudinal relationship with endothelial activation and cardiovascular risk markers.

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We aimed to determine whether people with human immunodeficiency virus (PWHIV) have increased measures of arterial injury [carotid intima-media thickness (cIMT)] and large artery stiffness [carotid-femoral pulse wave velocity (cfPWV)] […]

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The association between use of chemsex drugs and HIV clinic attendance among gay and bisexual men living with HIV in London.

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To investigate the association between chemsex drug use and HIV clinic attendance among gay and bisexual men in London.A cross-sectional survey of adults (> 18 years) diagnosed with HIV for > 4 months, attending […]

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Are Individuals with Substance Use Disorders at Higher Risk of SARS-CoV-2 Infection? Population-Based Registry Study in Northern Italy.

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This study assesses whether individuals with substance use disorder are at greater risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than people in the general population.A population-based study […]

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Care, crisis and coalition: imagining antiprophylactic citizenship through AIDS hospice activism.

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Using crip theory, specifically Barounis’ formulation of antiprophylactic citizenship, Piepzna-Samarasinha’s conceptualisation of care work, and Shotwell’s calls against purity, this paper analyses the making of the film HIV in the […]

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Dolutegravir Plus Lamivudine Two-Drug Regimen: Safety, Efficacy and Diagnostic Considerations for Its Use in Real-Life Clinical Practice-A Refined Approach in the COVID-19 Era.

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The diagnostic and therapeutic management of the Coronavirus Disease 2019 (COVID-19) pandemic in the HIV population brought some known criticalities (and opportunities) to the forefront, for both those who are […]

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Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant.

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The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants threatens progress toward control of the coronavirus disease 2019 (Covid-19) pandemic. In a phase 1-2 trial involving healthy adults, […]

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Adverse Psychological Reactions and Psychological Aids for Medical Staff During the COVID-19 Outbreak in China.

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Background: The outbreak of the novel coronavirus disease COVID-19 caused panic and psychological stress throughout the World. We investigated the extent of adverse psychological reactions in two medical staff groups […]

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Human immunodeficiency virus and mortality from coronavirus disease 2019: A systematic review and meta-analysis.

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Persons living with human immunodeficiency virus (PLWH) constitute a vulnerable population in view of their impaired immune status. At this time, the full interaction between HIV and severe acute respiratory […]

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Prevalence and Mortality due to COVID-19 in HIV Co-Infected Population: A Systematic Review and Meta-Analysis.

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The coronavirus disease 2019 (COVID-19) was defined as a species of beta coronavirus causing atypical respiratory disease in humans. The COVID-19 pandemic has resulted in an unprecedented health and economic […]

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SARS-CoV-2 seroprevalence, and IgG concentration and pseudovirus neutralising antibody titres after infection, compared by HIV status: a matched case-control observational study.

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Most cohorts show similar or lower COVID-19 incidence among people living with HIV compared with the general population. However, incidence might be affected by lower testing rates among vulnerable populations. […]

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Evolution of SARS-CoV-2 neutralizing antibody in an HIV-positive patient with COVID-19.

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We presented the clinical course and immune responses of a well-controlled HIV-positive patient with COVID-19. The clinical presentation and antibody production to SARS-CoV-2 were similar to other COVID-19 patients without […]

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