European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender.

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Lynch syndrome is the most common genetic predisposition for hereditary cancer but remains underdiagnosed. Large prospective observational studies have recently increased understanding of the effectiveness of colonoscopic surveillance and the […]

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A prospective, single-arm, multicenter trial of diverting stoma followed by neoadjuvant chemotherapy using mFOLFOX6 for obstructive colon cancer: YCOG 1305 (PROBE study).

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Obstructive colorectal cancer is locally advanced colorectal cancer with a poor prognosis. The effect of neoadjuvant chemotherapy for obstructive colon cancer is unclear.We conducted the first prospective clinical trial of […]

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Functional Dyspepsia and Irritable Bowel Syndrome are Highly Prevalent in Patients With Gallstones and are Negatively Associated With Outcomes After Cholecystectomy: A Prospective, Multicentre, Observational Study (PERFECT – Trial).

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To determine the prevalence of functional dyspepsia (FD) and irritable bowel syndrome (IBS) in patients eligible for cholecystectomy and to investigate the association between presence of FD/IBS and resolution of […]

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First Long-term Oncologic Results of the ALPPS Procedure in a Large Cohort of Patients With Colorectal Liver Metastases.

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To analyze long-term oncological outcome along with prognostic risk factors in a large cohort of patients with colorectal liver metastases (CRLM) undergoing ALPPS.ALPPS is a two-stage hepatectomy variant that increases […]

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Urgent surgical repair of symptomatic Bochdalek hernia containing an intrathoracic kidney.

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Bochdalek hernias rarely contain an intrathoracic kidney, and there are few reports of their operative repair. A woman presented with progressive dyspnoea limiting her quality of life. Imaging showed a […]

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Long-term Oncologic Results After Stenting as a Bridge to Surgery Versus Emergency Surgery for Malignant Left-sided Colonic Obstruction: A Multicenter Randomized Controlled Trial (ESCO Trial).

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To assess overall (OS), time to progression (TTP), and disease-free survival (DFS) at 3 years after treatment, comparing stenting as bridge-to-surgery (SBTS) versus emergency surgery (ES) in neoplastic left colon […]

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Choices of Therapeutic Strategies for Colorectal Liver Metastases Among Expert Liver Surgeons: A Throw of the Dice?

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To test the degree of agreement in selecting therapeutic options for patients suffering from colorectal liver metastasis (CRLM) among surgical experts around the globe.Only few areas in medicine have seen […]

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Prognosis of non-operative management of non-metastatic colorectal cancer in octa- and nonagenarians.

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The aim of the study was to establish the natural history of elderly patients with non-metastatic colorectal cancer who underwent non-operative management in comparison with those who underwent operative management.A […]

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Enhanced Recovery Pathway Benefits Patients Undergoing Nonelective Colorectal Surgery.

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MINI: Most published enhanced recovery pathways exclude patients undergoing urgent or emergent surgeries. This study found that nonelective colorectal surgery patients benefit significantly from the implementation of an enhanced recovery […]

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Development and Validation of an Image-based Deep Learning Algorithm for Detection of Synchronous Peritoneal Carcinomatosis in Colorectal Cancer.

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The aim of this study was to build a SVM classifier using ResNet-3D algorithm by artificial intelligence for prediction of synchronous PC.Adequate detection and staging of PC from CRC remain […]

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Cost-effectiveness Evaluation of Laparoscopic Versus Robotic Minimally Invasive Colectomy.

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Evaluate the cost-effectiveness of open, laparoscopic, and robotic colectomy.The use of robotic-assisted colon surgery is increasing. Robotic technology is more expensive and whether a robotically assisted approach is cost-effective remains […]

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Early Enteral Nutrition Following Gastrointestinal Surgery in Children: A Systematic Review of the Literature.

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To investigate the safety and effectiveness of early enteral feeding versus traditional enteral feeding after gastrointestinal (GI) anastomosis in children in the pediatric literature.Prolonged postoperative fasting has been the traditional […]

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C-reactive protein trajectory to predict colorectal anastomotic leak: PREDICT Study.

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Anastomotic leak is a common complication after colorectal surgery, associated with increased morbidity and mortality, and poorer long-term survival after oncological resections. Early diagnosis improves short-term outcomes, and may translate […]

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Risk Factors of Positive Resection Margin in Laparoscopic and Open Liver Surgery for Colorectal Liver Metastases: A New Perspective in the Perioperative Assessment: A European Multicenter Study.

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To assess the risk factors associated with R1 resection in patients undergoing OLS and LLS for CRLMs.The clinical impact of R1 resection in liver surgery for CRLMs has been continuously […]

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Post-discharge Opioid Consumption After Minimally Invasive and Open Colectomy: Does Operative Approach Matter?

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To determine if patients consume less opioid after minimally invasive colectomy compared to open colectomy.Opioids are overprescribed after surgery, and surgeons are under increasing pressure to reduce postoperative opioid prescribing. […]

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Frailty in older patients undergoing emergency colorectal surgery: USA National Surgical Quality Improvement Program analysis.

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Frailty is associated with advancing age and may result in adverse postoperative outcomes. A suspected growing elderly population needing emergency colorectal surgery stimulated this study of the prevalence and impact […]

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Evaluation of Recurrence Risk After Curative Resection for Patients With Stage I to III Colorectal Cancer Using the Hazard Function: Retrospective Analysis of a Single-institution Large Cohort.

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This study aimed to investigate transitions of recurrence hazard and peak recurrence time in patients with nonmetastatic CRC using the hazard function.A postoperative surveillance period of 5 years is consistent […]

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Ileus caused by small bowel, ileocaecal and rectal endometriosis misdiagnosed as Crohn’s disease and managed by synchronous ileocaecal and rectal resection.

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The reported incidence of intestinal endometriosis varies between 22% and 37%, with bowel obstruction in only 2.3% of cases, but few series report acute obstruction. We report a rare case […]

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Extensive pneumatosis intestinalis and portal venous gas mimicking mesenteric ischaemia in a patient with SARS-CoV-2.

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We present the case of a critically ill 47-year-old man diagnosed with SARS-CoV-2 (COVID-19) who developed extensive pneumatosis intestinalis and portal venous gas in conjunction with an acute abdomen during […]

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Primary colonic squamous cell carcinoma: a case report and review of the literature.

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Colonic squamous cell carcinoma is extremely rare, with no clear pathogenesis. It usually presents as an emergency. We present the surgical management of a descending colon squamous cell carcinoma, together […]

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A case of resected retroperitoneal metachronous solitary metastasis from caecal cancer.

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Colorectal cancer metastasis to the retroperitoneum, especially solitary metastasis allowing curative resection, is rare. We report a case of complete resection of retroperitoneal metachronous solitary metastasis from caecal cancer without […]

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Endoscopic tattooing for colorectal lesions: impact on quality of care and patient outcomes.

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The National Bowel Cancer Screening Programme guidelines advocate the use of endoscopic tattooing for suspected malignant lesions to assist identification and to facilitate laparoscopic resections. However, endoscopic tattooing practices are […]

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Small bowel obstruction due to splenosis 30 years after splenectomy.

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Splenosis is the autotransplantation of splenic tissue into abnormal locations due to trauma or iatrogenically. Usually, this causes no symptoms, but in rare cases the mass effect of the transplanted […]

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LekCheck: A Prospective Study to Identify Perioperative Modifiable Risk Factors for Anastomotic Leakage in Colorectal Surgery.

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To assess potentially modifiable perioperative risk factors for anastomotic leakage in adult patients undergoing colorectal surgery.Colorectal anastomotic leakage (CAL) is the single most important denominator of postoperative outcome after colorectal […]

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Effect of an individualized versus standard pneumoperitoneum pressure strategy on postoperative recovery: a randomized clinical trial in laparoscopic colorectal surgery.

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It remains uncertain whether individualization of pneumoperitoneum pressures during laparoscopic surgery improves postoperative recovery. This study compared an individualized pneumoperitoneum pressure (IPP) strategy with a standard pneumoperitoneum pressure (SPP) strategy with respect to […]

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Current technical surgical practice of emergency appendicectomy: a cross-sectional survey of surgical registrars in the UK.

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Appendicectomy remains one of the most commonly performed procedures in general surgery. The aim of this study was to explore variation in operative techniques of an appendicectomy among surgical registrars […]

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Impact of rectal perforation on recurrence during rectal cancer surgery in a national population registry.

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Incidental perforation in rectal cancer surgery is considered a risk factor for poorer oncological outcome. Most studies emanate from the era before total mesorectal excision when staging, neoadjuvant treatment and […]

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