Effects of IVF therapies on metabolic, endocrine and inflammatory status in IVF-conceived pregnancy.

Bookmark(0)

No account yet? Register

In vitro fertilization (IVF) is a common treatment for infertility. In mice, IVF is associated with development of glucose intolerance. However, human data are limited regarding the metabolic, endocrine and […]

» Read more

Individual and Combined Associations of Modifiable Lifestyle and Metabolic Health Status With New-Onset Diabetes and Major Cardiovascular Events: The China Cardiometabolic Disease and Cancer Cohort (4C) Study.

Bookmark(0)

No account yet? Register

We aimed to determine the individual and combined associations of lifestyle and metabolic factors with new-onset diabetes and major cardiovascular events among a Chinese population aged ≥40 years.Baseline lifestyle information, […]

» Read more

Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study.

Bookmark(0)

No account yet? Register

We aimed to examine associations of cardiometabolic risk factors, and (pre)diabetes, with (sensorimotor) peripheral nerve function.In 2401 adults (aged 40-75 years) we previously determined fasting glucose, HbA1c, triacylglycerol, HDL- and LDL-cholesterol, […]

» Read more

Vasculometabolic and Inflammatory Effects of Aldosterone in Obesity.

Bookmark(0)

No account yet? Register

Not all obese individuals develop cardiovascular disease (CVD). Hyperaldosteronism is suggested to cause inflammation and metabolic dysregulation, and might contribute to CVD development in obese individuals.We aimed to investigate the […]

» Read more

Metabolic Effects of Late Dinner in Healthy Volunteers – A Randomized Crossover Clinical Trial.

Bookmark(0)

No account yet? Register

Consuming calories later in the day is associated with obesity and metabolic syndrome. We hypothesized that eating a late dinner alters substrate metabolism during sleep in a manner that promotes […]

» Read more

Ketone Body, 3-hydroxybutyrate: Minor Metabolite – Major Medical Manifestations.

Bookmark(0)

No account yet? Register

Ketone bodies – 3-hydroxybutyrate (3-OHB), acetoacetate and acetone – are ancient, evolutionarily preserved, small fuel substrates, which uniquely can substitute and alternate with glucose under conditions of fuel and food […]

» Read more

Serum profile of microRNAs linked to bone metabolism during sequential treatment for postmenopausal osteoporosis.

Bookmark(0)

No account yet? Register

Serum expression of microRNAs (miRs) related to bone metabolism is affected by anti-osteoporotic treatment.To investigate the effect of sequential treatments on miRs expression in postmenopausal women with osteoporosis.Observational, open label, […]

» Read more

Insulin Sensitizers for Improving the Endocrine and Metabolic Profile in Overweight Women with PCOS.

Bookmark(0)

No account yet? Register

To evaluate the efficacy of insulin sensitizers on menstrual frequency, sex hormone and metabolic parameters in overweight women with PCOS.We searched multiple databases from inception to September 2019 for RCTs. […]

» Read more

Effects of Sustained Treatment With Lixisenatide on Gastric Emptying and Postprandial Glucose Metabolism in Type 2 Diabetes: A Randomized Controlled Trial.

Bookmark(0)

No account yet? Register

Tachyphylaxis for slowing of gastric emptying is seen with continuous exposure to glucagon-like peptide 1 (GLP-1). We therefore aimed to establish whether prolonged use of a “short-acting” GLP-1 receptor agonist, […]

» Read more

Health Care Costs Associated With Macrovascular, Microvascular, and Metabolic Complications of Type 2 Diabetes Across Time: Estimates From a Population-Based Cohort of More Than 0.8 Million Individuals With Up to 15 Years of Follow-up.

Bookmark(0)

No account yet? Register

Developing country-specific unit-cost catalogs is a key area for advancing economic research to improve medical and policy decisions. However, little is known about how health care costs vary by type […]

» Read more

Longitudinal study on metabolic health in SGA adults during 5 years after GH with or without 2 years of GnRHa treatment.

Bookmark(0)

No account yet? Register

In children born small for gestational age (SGA) with persistent short stature, 2 years of gonadotropin-releasing hormone analogue (GnRHa), in addition to long-term growth hormone (GH) treatment, can improve adult […]

» Read more

Mitochondrial nutrient utilization underlying the association between metabolites and insulin resistance in adolescents.

Bookmark(0)

No account yet? Register

A person’s intrinsic metabolism, reflected in the metabolome, may describe the relationship between nutrient intake and metabolic health.Untargeted metabolomics was used to identify metabolites associated with metabolic health. Path analysis […]

» Read more

Bone and mineral metabolism in children with nephropathic cystinosis compared to other CKD entities.

Bookmark(0)

No account yet? Register

Children with nephropathic cystinosis (NC) show persistent hypophosphatemia, due to Fanconi syndrome, as well as mineral and bone disorders related to chronic kidney disease (CKD), but systematic analyses are lacking.To […]

» Read more

Exercise training reduces inflammatory metabolic activity of visceral fat assessed by 18 F-FDG PET/CT in obese women.

Bookmark(0)

No account yet? Register

Obesity plays pivotal roles in the increased risk of cardiometabolic disease via induction of the inflammatory reaction from macrophages in visceral adipose tissue (VAT), which may elevate the inflammatory activity […]

» Read more

Early Metabolic Features of Genetic Liability to Type 2 Diabetes: Cohort Study With Repeated Metabolomics Across Early Life.

Bookmark(0)

No account yet? Register

Type 2 diabetes develops for many years before diagnosis. We aimed to reveal early metabolic features characterizing liability to adult disease by examining genetic liability to adult type 2 diabetes […]

» Read more

Human bone marrow adipose tissue is a metabolically active and insulin sensitive distinct fat depot.

Bookmark(0)

No account yet? Register

Bone marrow (BM) in adult long bones is rich in adipose tissue, but the functions of BM adipocytes are largely unknown. We set out to elucidate the metabolic and molecular […]

» Read more

The impact of disuse and high-fat overfeeding on forearm muscle amino acid metabolism in humans.

Bookmark(0)

No account yet? Register

Anabolic resistance is mechanistically implicated in muscle disuse atrophy.Assess whether anabolic resistance is associated with reduced postprandial amino acid uptake or exacerbated by excess lipid availability.Twenty men underwent 7 days […]

» Read more

Metabolic Factors, Lifestyle Habits, and Possible Polyneuropathy in Early Type 2 Diabetes: A Nationwide Study of 5,249 Patients in the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Cohort.

Bookmark(0)

No account yet? Register

To investigate the association of metabolic and lifestyle factors with possible diabetic polyneuropathy (DPN) and neuropathic pain in patients with early type 2 diabetes.We thoroughly characterized 6,726 patients with recently […]

» Read more

Racial and ethnic differences in the metabolic response of polycystic ovary syndrome.

Bookmark(0)

No account yet? Register

Polycystic ovary syndrome (PCOS) is a highly prevalent disorder associated with insulin resistance (IR) and compensatory hyperinsulinemia. Although variations in cardiometabolic risks across race and ethnicities have been reported in […]

» Read more
1 2 3 6