Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline.

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This guideline will provide the practicing endocrinologist with an approach to assessment and treatment of dyslipidemia in patients with endocrine diseases, with the objective of prevention of cardiovascular events and […]

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Predictors of the Response to Dopaminergic Therapy in Patients with Prolactinoma.

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Withdrawal of dopamine agonist (DA) therapy in patients with prolactinoma who are controlled by a small dose of medication is recommended by several guidelines. So far, the likelihood of reaching […]

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A systematic review of anti-androgens and feminisation in transgender women.

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Anti-androgens are frequently used with estradiol in transgender women seeking feminisation. Anti-androgens act by various mechanisms to decrease the production or effects of testosterone, but it is unclear which anti-androgen […]

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The Evolution of the Primary Aldosteronism Syndrome: Updating the Approach.

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New approaches are needed to address the evolution of the primary aldosteronism syndrome and to increase its recognition. Herein, we review evidence indicating that primary aldosteronism is a prevalent syndrome […]

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Gestational diabetes: opportunities for improving maternal and child health.

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Gestational diabetes, the most common medical disorder in pregnancy, is defined as glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in pregnancy. Gestational diabetes is associated with […]

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Distant metastasis in pediatric and adolescent differentiated thyroid cancer: Clinical outcomes and risk factor analyses.

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The specific characteristics of pediatric and adolescent differentiated thyroid cancer (DTC) is the more frequent occurrence of distant metastasis (DM) compared with adult DTC.To investigate the clinical outcomes of DM […]

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Management and appropriate use of diazoxide in infants and children with hyperinsulinism.

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The diagnosis of hypoglycemia and the use of diazoxide have risen in the last decade. Diazoxide is the only FDA-approved pharmacologic treatment for neonatal hypoglycemia caused by hyperinsulinism (HI). Recent […]

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Normocalcemic Primary Hyperthyroidism: An Update on Diagnostic and Management Challenges.

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Normocalcemic primary hyperparathyroidism likely represents a condition that may evolve into its hypercalcemic counterpart and recent studies have shown that patients can present with intermittent hypercalcemia. This milder biochemical entity […]

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Evaluation of the Role of Thyroid Scintigraphy in the Differential Diagnosis of Thyrotoxicosis.

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A differential diagnosis of thyrotoxicosis is crucial as the treatment of the main causes of this condition can vary significantly. Recently published diagnostic guidelines on thyrotoxicosis embrace the presence of […]

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A personalised screening strategy for diabetic retinopathy: a cost-effectiveness perspective.

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In this study we examined the cost-effectiveness of three different screening strategies for diabetic retinopathy: using a personalised adaptive model, annual screening (fixed intervals), and the current Dutch guideline (stratified […]

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Prevalence of Latent and Overt Polyautoimmunity in Autoimmune Thyroid Disease: A Systematic Review and Meta-analysis.

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Thyroid autoimmunity is the most frequent condition involved in polyautoimmunity (PolyA). However, the frequency of latent and overt PolyA in patients with autoimmune thyroid disease (AITD) as the index condition […]

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International histopathology consensus for unilateral primary aldosteronism.

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Develop a consensus for the nomenclature and definition of adrenal histopathologic features in unilateral primary aldosteronism (PA).Unilateral PA is the most common surgically-treated form of hypertension. Morphologic examination combined with […]

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Relation of Health-related Quality of life to near final height and body composition in adolescents with chronic endocrinopathies during transition period.

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We evaluated sequelae of disease and therapy in adolescents with chronic endocrinopathies using a medical and psychological work-up to record Health related Quality of Life (HRQoL), near final heights (NFH), […]

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Challenges in preventing bone loss induced by aromatase inhibitors.

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Aromatase inhibitors have become a mainstay in the adjuvant treatment regime in postmenopausal women with hormone-receptor positive breast cancer. While many of these patients have an excellent long-term prognosis, adverse […]

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The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Management of Blood Cholesterol in Diabetes.

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The American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines recently published its 2018 recommendations on management of LDL cholesterol (LDL-C) in people with diabetes. For primary […]

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COVID-19 in people living with diabetes: An international consensus.

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The COVID-19 pandemic has added an enormous toll to the existing challenge of diabetes care world-wide. A large proportion of patients with COVID-19 requiring hospitalization and/or succumbing to the disease […]

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The Association Between HbA1c and Time in Hypoglycemia During CGM and Self-Monitoring of Blood Glucose in People With Type 1 Diabetes and Multiple Daily Insulin Injections: A Randomized Clinical Trial (GOLD-4).

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According to recent guidelines, individuals with type 1 diabetes should spend <4.0% per day with glucose levels <3.9 mmol/L (<70 mg/dL) and <1.0% per day with glucose levels <3.0 mmol/L […]

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Primary care provider involvement in thyroid cancer survivorship care.

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To understand PCP involvement and confidence in thyroid cancer survivorship care.Setting/Participants: We surveyed PCPs identified by thyroid cancer patients from the Georgia and LA SEER registries (n=162, response rate 56%). […]

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Effect of Diet on Insulin Resistance in Polycystic Ovary Syndrome.

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The effect of diet on insulin resistance (IR) in polycystic ovary syndrome (PCOS) is controversial. Thus, we conducted this systematic review and meta-analysis to evaluate whether diet could reduce IR […]

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Temporal Trend in Young-Onset Type 2 Diabetes-the Macrovascular and Mortality Risk: Study of U.K. Primary Care Electronic Medical Records.

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To evaluate temporal prevalence trend, cardiometabolic risk factors, and the risk of atherosclerotic cardiovascular disease (ASCVD) and all-cause mortality (ACM) in incident young- and usual-onset type 2 diabetes.From the U.K. […]

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The vicious circle of left ventricular dysfunction and diabetes: from pathophysiology to emerging treatments.

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Diabetes and heart failure (HF) are two deadly and strictly related epidemic disorders. Aim of this review is to present an updated discussion of the epidemiology, pathophysiology, clinical presentation and […]

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Key Strategies for Clinical Management and Improvement of Healthcare Services for Cardiovascular Disease and Diabetes Patients in the Coronavirus (COVID-19) Settings: Recommendations From the REPROGRAM Consortium.

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Patients with cardiovascular disease and diabetes are at potentially higher risk of infection and fatality due to COVID-19. Given the social and economic costs associated with disability due to these […]

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Temporary changes in clinical guidelines of gestational diabetes screening and management during COVID-19 outbreak: A narrative review.

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New clinical approaches are needed to minimize complications of gestational diabetes during the COVID-19 outbreak with timely screening and proper management. The present study aims to highlight changes in the […]

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Prescribing Paradigm Shift? Applying the 2019 European Society of Cardiology-Led Guidelines on Diabetes, Prediabetes, and Cardiovascular Disease to Assess Eligibility for Sodium-Glucose Cotransporter 2 Inhibitors or Glucagon-Like Peptide 1 Receptor Agonists as First-Line Monotherapy (or Add-on to Metformin Monotherapy) in Type 2 Diabetes in Scotland.

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In 2019, the European Society of Cardiology led and released new guidelines for diabetes cardiovascular (CV) risk management, reflecting recent evidence of CV disease (CVD) reduction with sodium-glucose cotransporter 2 […]

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Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

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The convergence of advances in medical science, human biology, data science, and technology has enabled the generation of new insights into the phenotype known as “diabetes.” Increased knowledge of this […]

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Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

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The convergence of advances in medical science, human biology, data science and technology has enabled the generation of new insights into the phenotype known as ‘diabetes’. Increased knowledge of this […]

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