Prehospital clinical signs are a poor predictor of raised intracranial pressure following traumatic brain injury.

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For the prehospital diagnosis of raised intracranial pressure (ICP), clinicians are reliant on clinical signs such as the Glasgow Coma Score (GCS), pupillary response and/or Cushing’s triad (hypertension, bradycardia and […]

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Thromboelastography and Rotational Thromboelastometry in Bleeding Patients with Coagulopathy: Practice Management Guideline from the Eastern Association for the Surgery of Trauma.

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Assessment of the immediate need for specific blood product transfusions in acutely bleeding patients is challenging. Clinical assessment and commonly used coagulation tests are inaccurate and time-consuming. The goal of […]

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End-tidal and arterial carbon dioxide gradient in serious traumatic brain injury after prehospital emergency anaesthesia: a retrospective observational study.

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In the UK, 20% of patients with severe traumatic brain injury (TBI) receive prehospital emergency anaesthesia (PHEA). Current guidance recommends an end-tidal carbon dioxide (ETCO2) of 4.0-4.5 kPa (30.0-33.8 mm Hg) to […]

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Association of Intra-arrest Transport vs Continued On-Scene Resuscitation With Survival to Hospital Discharge Among Patients With Out-of-Hospital Cardiac Arrest.

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There is wide variability among emergency medical systems (EMS) with respect to transport to hospital during out-of-hospital cardiac arrest (OHCA) resuscitative efforts. The benefit of intra-arrest transport during resuscitation compared […]

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Plasmin TEG Rapidly Identifies Trauma Patients at Risk for Massive Transfusion, Mortality and Hyperfibrinolysis: A Diagnostic Tool to Resolve an International Debate on TXA?

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Trauma patients with hyperfibrinolysis and depletion of fibrinolytic inhibitors(DFI) measured by thrombelastography(TEG) gain clot strength with TXA, but TEG results take nearly an hour. We aimed to develop an assay, […]

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Application of the Modified NUTRIC (mNUTRIC) Score to Nutritional Risk Stratification of Trauma Victims: A multicenter observational study.

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The modified Nutrition Risk in Critically ill (mNUTRIC) score was developed to identify patients most likely to benefit from nutritional therapies and to stratify or select study subjects for clinical […]

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Timing of invasive mechanic ventilation in critically ill patients with coronavirus disease 2019.

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Invasive mechanical ventilation (IMV) is a lifesaving strategy for critically ill patients with coronavirus disease 2019 (COVID-19). We aim to report the case series of critical patients receiving IMV in […]

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The critical threshold value of systolic blood pressure for aortic occlusion in trauma patients in profound hemorrhagic shock.

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To determine the critical threshold of systolic blood pressure (SBP) for aortic occlusion (AO) in severely injured patients with profound hemorrhagic shock.All adult patients (>15 years) undergoing AO via Resuscitative […]

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Prospective Study of Short-Term Quality-of-Life After Traumatic Rib Fractures.

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Post-discharge convalescence after traumatic rib fractures remains unclear. We hypothesized that patients with rib fractures, even as an isolated injury, have associated poor QoL after discharge.We prospectively enrolled adult patients […]

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Regionalization of Trauma Care by Operative Experience: Does the Volume of Emergent Laparotomy Matter?

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The volume-outcome relationship led to the regionalization of trauma care. The relationship between trauma centers’ injury-specific laparotomy volume and outcomes has not been explored. The aim of our study was […]

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Comparing GIS-based estimates with trauma center registry data to assess the effects of additional trauma centers on system access.

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Geographic information systems (GIS) are often used to analyze trauma systems. GIS-based approaches can model access to a trauma center (TC), including estimates of transport time and population coverage, when […]

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The management of occult hemothorax in adults with thoracic trauma: a systematic review and meta-analysis.

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Hemothorax is a common sequelae following thoracic trauma and is associated with significant morbidity and mortality. Current guidelines recommend all traumatic hemothoraces be considered for drainage with tube thoracostomy (TT), […]

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Plasmin TEG Rapidly Identifies Trauma Patients at Risk for Massive Transfusion, Mortality and Hyperfibrinolysis: A Diagnostic Tool to Resolve an International Debate on TXA?

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Trauma patients with hyperfibrinolysis and depletion of fibrinolytic inhibitors(DFI) measured by thrombelastography(TEG) gain clot strength with TXA, but TEG results take nearly an hour. We aimed to develop an assay, […]

» Read more

Application of the Modified NUTRIC (mNUTRIC) Score to Nutritional Risk Stratification of Trauma Victims: A multicenter observational study.

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The modified Nutrition Risk in Critically ill (mNUTRIC) score was developed to identify patients most likely to benefit from nutritional therapies and to stratify or select study subjects for clinical […]

» Read more

Regionalization of Trauma Care by Operative Experience: Does the Volume of Emergent Laparotomy Matter?

Bookmark this %label%

The volume-outcome relationship led to the regionalization of trauma care. The relationship between trauma centers’ injury-specific laparotomy volume and outcomes has not been explored. The aim of our study was […]

» Read more

The critical threshold value of systolic blood pressure for aortic occlusion in trauma patients in profound hemorrhagic shock.

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To determine the critical threshold of systolic blood pressure (SBP) for aortic occlusion (AO) in severely injured patients with profound hemorrhagic shock.All adult patients (>15 years) undergoing AO via Resuscitative […]

» Read more

Comparing GIS-based estimates with trauma center registry data to assess the effects of additional trauma centers on system access.

Bookmark this %label%

Geographic information systems (GIS) are often used to analyze trauma systems. GIS-based approaches can model access to a trauma center (TC), including estimates of transport time and population coverage, when […]

» Read more

Prospective Study of Short-Term Quality-of-Life After Traumatic Rib Fractures.

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Post-discharge convalescence after traumatic rib fractures remains unclear. We hypothesized that patients with rib fractures, even as an isolated injury, have associated poor QoL after discharge.We prospectively enrolled adult patients […]

» Read more

The management of occult hemothorax in adults with thoracic trauma: a systematic review and meta-analysis.

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Hemothorax is a common sequelae following thoracic trauma and is associated with significant morbidity and mortality. Current guidelines recommend all traumatic hemothoraces be considered for drainage with tube thoracostomy (TT), […]

» Read more

Emergency care provided to refugee children in Europe: RefuNET: a cross-sectional survey study.

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Refugee children and young people have complex healthcare needs. However, issues related to acute healthcare provision for refugee children across Europe remain unexplored. This study aimed to describe the urgent […]

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Risk of significant traumatic brain injury in adults with minor head injury taking direct oral anticoagulants: a cohort study and updated meta-analysis.

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Patients taking direct oral anticoagulants (DOACs) commonly undergo CT head imaging after minor head injury, regardless of symptoms or signs. However, the risk of intracranial haemorrhage (ICH) in such patients […]

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PLASMA RESUSCITATION WITH ADJUNCTIVE PERITONEAL RESUSCITATION REDUCES ISCHEMIA-INDUCED INTESTINAL BARRIER BREAKDOWN FOLLOWING HEMORRHAGIC SHOCK.

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Hemorrhagic shock and resuscitation (HS/RES) causes ischemia-induced intestinal permeability due to intestinal barrier breakdown, damage to the endothelium, and tight junction (TJ) complex disruption between enterocytes. The effect of hemostatic […]

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Use of Fibrinogen Concentrate for Trauma-Related Bleeding: A Systematic-Review and Meta-Analysis.

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Trauma-induced coagulopathy contributes to significant morbidity and mortality in patients who experience trauma-related bleeding.To synthesize the evidence supporting the efficacy and safety of preemptive and goal-directed fibrinogen concentrate (FC) in […]

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Association of Timing of Initiation of Pharmacologic Venous Thromboembolism Prophylaxis with Outcomes in Trauma Patients.

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Patients are at a high risk for developing venous thromboembolism (VTE) following traumatic injury. We examined the relationship between timing of initiation of pharmacologic prophylaxis with VTE complications.Trauma quality collaborative […]

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Valproic Acid Treatment Rescues Injured Tissues After Traumatic Brain Injury.

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No agents that are specifically neuroprotective are currently approved to emergently treat patients with traumatic brain injury (TBI). The histone deacetylase inhibitor, high-dose valproic acid (VPA) has been shown to […]

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