Height, nevus count, and risk of cutaneous malignant melanoma: results from two large cohorts of US women.

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Taller individuals are at higher risk of melanoma.To prospectively investigate the association of height with nevus count and melanoma and estimate the proportion of height-melanoma association explained by nevus count […]

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Clinical and dermoscopic characteristics of congenital and non-congenital nevus-associated melanomas.

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No specific features of nevus-associated melanoma (NAM) are currently defined.To identify clinical/dermoscopic features of NAM.Retrospective evaluation of histopathologically diagnosed NAM.80/165 NAMs had a clinically recognizable nevus component, often raised or […]

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Technological advances for the detection of melanoma: Part II. Advances in molecular techniques.

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The growth of molecular technologies analyzing skin cells and inherited genetic variations has the potential to address current gaps in both diagnostic accuracy and prognostication in melanoma patients or in […]

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Technological advances for the detection of melanoma: Part I. Advances in diagnostic techniques.

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Managing the balance between accurately identifying early-stage melanomas while avoiding biopsies of benign lesions (i.e. over-biopsy) is the major challenge of melanoma detection. Decision-making can be especially difficult in patients […]

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Survival in Patients with Multiple Primary Melanomas: Systematic Review and Meta-analysis.

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The literature surrounding survival of patients with multiple primary melanomas (MPM) yields variable and opposing findings, constrained by statistical challenges.To critically examine the available literature regarding survival of patients with […]

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Molecular risk prediction in cutaneous melanoma: a meta-analysis of the 31-gene expression profile prognostic test in 1,479 patients.

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Multiple studies have reported on the accuracy of the prognostic 31-gene expression profile test (31-GEP) for cutaneous melanoma. Consistency of the test results across studies has not been systematically evaluated.To […]

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The association between partner bereavement and melanoma: cohort studies in the U.K. and Denmark.

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Psychological stress is commonly cited as a risk factor for melanoma, but clinical evidence is limited.This study aimed to evaluate the association between partner bereavement and (i) first-time melanoma diagnosis […]

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Malignant melanoma of the breast: controversies in the diagnosis and therapeutic management of a rare nosologic entity.

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Melanoma of the breast is an infrequent entity, presenting as either primary or metastatic from extramammary solid neoplasms. Depending on the involvement of the skin, primary malignant melanoma of the […]

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Real world outcomes of melanoma surveillance using the MoleMap NZ telemedicine platform.

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MoleMap NZ is a novel New Zealand based store-and-forward telemedicine service to detect melanoma. It utilizes expert review of total body photography and close-up and dermoscopic images of skin lesions […]

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Melanoma incidence, stage, and survival after solid organ transplant: A population-based cohort study in Ontario, Canada.

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Risk of melanoma is increased with potentially worse outcomes after solid organ transplant.To estimate the incidence, stage, and survival in transplant recipients with melanoma.Population-based, retrospective, observational study using linked administrative […]

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Differing biologic behaviors of Desmoplastic melanoma subtypes – insights based on histopathological, immunohistochemical and genetic analyses.

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Desmoplastic melanoma (DM) is an uncommon variant of melanoma that can be challenging to diagnose. Phenotypic variations in terms of the proportion of spindled cells and fibromucinous stroma have led […]

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Skin Cancer and Skin Cancer Risk Behaviors Among Sexual and Gender Minority Populations: A Systematic Review.

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Sexual and gender minority individuals may have different lifetime risk of skin cancer and ultraviolet radiation exposure than heterosexual persons.To systematically review the prevalence of skin cancer and behaviors that […]

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GNAQ and GNA11 mutant non-uveal melanoma, a subtype distinct from both cutaneous and uveal melanoma.

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GNAQ and GNA11 mutant non-uveal melanoma represent a poorly characterized, rare subgroup of melanoma with a gene mutation profile similar to uveal melanoma.To characterize these tumours in terms of clinical […]

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