Use of beta-blockers for rosacea-associated facial erythema and flushing: a systematic review and update on proposed mode of action.

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Flushing and erythema are frequent skin symptoms in rosacea. As their adequate treatment remains a clinical challenge, new treatment options are explored, such as oral β-blockers.To evaluate the efficacy of […]

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Association between Rosacea and Cardiometabolic Disease: A Systematic Review and Meta-Analysis.

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Rosacea is recognized as a chronic inflammatory cutaneous disorder associated with multiple systemic illnesses. However, the association between rosacea and cardiometabolic disease (CMD) remains controversial.To evaluate the association between rosacea […]

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Standard Management Options for Rosacea: the 2019 Update by the National Rosacea Society Expert Committee.

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In 2017 a National Rosacea Society expert committee developed and published an updated classification of rosacea to reflect current insights into rosacea pathogenesis, pathophysiology, and management. These developments suggest that […]

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Minocycline 1.5% Foam for the Topical Treatment of Moderate-to-Severe Papulopustular Rosacea: Results of Two Phase 3, Randomized, Clinical Trials.

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Efficacious topical medications for rosacea are needed. FMX103 1.5% is a novel, topical minocycline foam that may have therapeutic benefits in treating rosacea, while minimizing systemic side effects due to […]

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First reported cases of Actinic folliculitis treated successfully with topical retinoid.

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Actinic Folliculitis (AF) is a rare recurrent seasonal photodermatosis, relatively newly characterised by non pruritic, monomorphic pustules and papules appearing 4 – 24 hours after exposure to sunlight. Lesions usually […]

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Dermoscopy of idiopathic facial aseptic granuloma: report of 2 cases.

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Idiopathic facial aseptic granuloma (IFAG) is an uncommon childhood condition, characterized by one or more asymptomatic erythematous-violaceous nodules, usually located on the cheeks and eyelid [1]. IFAG heals spontaneously usually […]

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A Multicenter, Randomized, Double-Masked, Parallel Group, Vehicle-Controlled Phase 2b Study to evaluate the safety and efficacy of 1% and 3% topical Minocycline Gel in patients with Papulopustular Rosacea.

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Papulopustular rosacea is characterized by chronic facial erythema and inflammatory facial lesions. Minocycline has anti-inflammatory properties which may be effective in the treatment of rosacea inflammatory lesions.To assess the safety […]

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Rosacea: a wholistic review and update from pathogenesis to diagnosis and therapy.

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Rosacea is a chronic inflammatory disorder of the central face with multiple overlapping presentations. Recent advancements are reshaping our understanding of rosacea from both a pathophysiologic perspective and clinical approach […]

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Recommendations for rosacea diagnosis, classification and management: Update from the global ROSacea COnsensus (ROSCO) 2019 panel.

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Abstract: A transition from subtyping to a phenotyping approach in rosacea is underway, allowing individual patient management according to presenting features instead of categorisation by pre-defined subtypes. The ROSCO 2017 […]

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Vascular endothelial growth factor gene polymorphisms in patients with rosacea: A case-control study.

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Abstract: Rosacea is a chronic disease that is characterized by facial skin inflammation and vascular abnormality. Vascular endothelial growth factor (VEGF) is a potent mediator of vascular permeability and inflammation […]

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A randomized phase 3b/4 study to evaluate concomitant use of topical ivermectin 1% cream and doxycycline 40 mg modified-release capsules versus topical ivermectin 1% cream and placebo in the treatment of severe rosacea.

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Abstract: Randomized controlled studies of combination therapies in rosacea are limited.Evaluate efficacy and safety of combining ivermectin 1% cream (IVM) and doxycycline 40 mg modified-release capsules? (DMR) versus IVM and […]

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