Children of the Sun: a historical look at how pediatric light therapy shaped attitudes and behaviors toward sunbathing.

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Today, parents are warned to protect their children from the sun’s ultraviolet (UV) rays, the most preventable and leading cause of skin cancer. Yet, during the first half of the […]

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What are the best endpoints for Eczema Area and Severity Index and Scoring Atopic Dermatitis in clinical practice? A prospective observational study.

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Multiple strategies have been used to evaluate the minimal important change (MIC) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis (SCORAD). The meaningfulness of these MICs […]

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Symptom burden of atopic dermatitis in early childhood assessed from daily monitoring of symptoms and topical steroid usage.

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Disease burden of atopic dermatitis (AD) as number of days with symptoms and medical treatment has never been studied as measure of severity.To investigate risk factors for AD burden in […]

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An economic evaluation of the randomised controlled trial of topical corticosteroid and home-based narrowband UVB for active and limited vitiligo (The HI-Light Trial).

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Economic evidence for vitiligo treatments is absent.To determine the cost-effectiveness of (a) hand-held narrowband-UVB (NB-UVB) and (b) combination of topical corticosteroid (TCS) and NB-UVB compared to TCS for localised vitiligo.Cost-effectiveness […]

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What’s new in atopic eczema? An analysis of systematic reviews published in 2018. Part 1: prevention and topical therapies.

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This review is part of a series of annual updates that summarize the evidence base for atopic eczema (AE). The aim is to provide a succinct guide for clinicians on […]

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Capillary malformation-arteriovenous malformation syndrome. A multicenter study.

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Capillary malformation-arteriovenous malformation (CM-AVM) syndrome is a rare syndrome that associates characteristic skin lesions with fast-flow vascular malformations (FFVM) in one-third of patients. Few case series have been described, and none […]

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Diagnosis of Mycoplasma aetiology in Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.

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We were pleased that the first national guidelines for paediatric Stevens-Johnson Syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) were published in your journal last year1 . They highlighted the higher […]

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Shades of grey: what is paediatric psoriasiform dermatitis and what does it have in common with childhood psoriasis?

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While the majority of children with a chronic itchy rash suffer from atopic dermatitis (AD) and other forms of dermatitis, psoriasis is in the differential diagnosis. Certain patterns such as […]

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Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya: a systematic review and meta-analysis.

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Background Increasing numbers of neonates are undergoing painful procedures in low-income and middle-income countries, with adequate analgesia seldom used. In collaboration with a multi-disciplinary team in Kenya, we aimed to […]

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Development of locally relevant clinical guidelines for procedure-related neonatal analgesic practice in Kenya: a systematic review and meta-analysis.

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Background Increasing numbers of neonates are undergoing painful procedures in low-income and middle-income countries, with adequate analgesia seldom used. In collaboration with a multi-disciplinary team in Kenya, we aimed to […]

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Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study.

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The risk of vertical and perinatal transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, which causes COVID-19), the most appropriate management, and the neonate’s risk of developing COVID-19 during […]

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Prostaglandin D2 metabolite is not a useful clinical indicator for assessing atopic dermatitis.

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Prostaglandin D2 (PGD2 ) plays an important role in atopic dermatitis (AD) and 11, 15-dioxo-9α-hydroxy-, 2, 3, 4, 5-tetranorprostan-1, 20-dioicacid (PGDM) is a major metabolite of PGD2 . We investigated […]

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Clinical presentation, sonographic features and treatment options of segmental stiff skin syndrome: a case series.

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Segmental stiff skin syndrome (SSSS) is a rare genetic connective tissue disease, which is often misdiagnosed. High-frequency ultrasonography can represent a useful clinical adjunct in the differential diagnosis of this […]

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Intensive care needs and long-term outcome of pediatric toxic epidermal necrolysis – A 10-year experience.

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Toxic epidermal necrolysis (TEN) is a life-threatening severe cutaneous adverse reaction. Data on pediatric TEN is limited.Case records of 44 children, 1 month-12 years with a diagnosis of TEN (>30% body surface […]

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Cutaneous Reactions in Children Treated with MEK Inhibitors, BRAF Inhibitors, or Combination Therapy: A Multi-Center Study.

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Treatment with BRAFI and MEKI causes cutaneous reactions in children limiting dosing or resulting in treatment cessation. The spectrum and severity of theses reactions is not defined.To determine the frequency […]

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Transcutaneous bilirubinometry during and after phototherapy in preterm infants: a prospective observational study.

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To examine the accuracy of transcutaneous bilirubinometry (TCB) measurements during and after phototherapy (PT) in preterm infants.Prospective observational cohort study.Level III neonatal centre.Preterm infants (from 23+0 to 36+6 weeks of […]

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Scabies coexisting with other dermatoses: the importance of recognizing multiple pathologies in resource-poor settings.

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Background Skin Neglected Tropical Diseases (NTDs) are a group of ten diseases often co-endemic in African rural communities and characterized by primary skin involvement. If not diagnosed and treated promptly, […]

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A Retrospective Multicenter Study of Fatal Pediatric Melanoma.

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Pediatric melanoma is rare and diagnostically challenging.Characterize clinical and histopathological features of fatal pediatric melanomas.Multi-center retrospective study of fatal melanoma cases in patients under 20 years diagnosed between 1994-2017.Of 38 […]

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