Pain management in hidradenitis suppurativa and a proposed treatment algorithm.

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Pain contributes substantially to reduced quality of life in individuals living with hidradenitis suppurativa (HS). Although improved understanding of HS pathogenesis and treatment has resulted in improved evidence-based HS management […]

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The Alopecia Areata Consensus of Experts (ACE) Study PART II: Results of an International Expert Opinion on Diagnosis and Laboratory Evaluation for Alopecia Areata.

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We previously reported The Alopecia Areata Consensus of Experts (ACE) Study: Results of an International Expert Opinion on Treatments for Alopecia Areata (AA).To report the results of the ACE international […]

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The Alopecia Areata Consensus of Experts (ACE) Study PART II: Results of an International Expert Opinion on Diagnosis and Laboratory Evaluation for Alopecia Areata.

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We previously reported The Alopecia Areata Consensus of Experts (ACE) Study: Results of an International Expert Opinion on Treatments for Alopecia Areata (AA).To report the results of the ACE international […]

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Research priorities and identification of a health-service delivery model for psoriasis from the UK Psoriasis Priority Setting Partnership.

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Psoriasis impacts the health and psychosocial functioning of patients, conferring a significant economic burden on healthcare systems. There remain unmet needs in psoriasis care, which if addressed by research, could […]

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Diagnosis of Mycoplasma aetiology in Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.

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We were pleased that the first national guidelines for paediatric Stevens-Johnson Syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) were published in your journal last year1 . They highlighted the higher […]

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fJoint AAD-NPF Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity measures.

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Psoriasis is a chronic, inflammatory, multisystem disease which affects up to 3.2% of the U.S population. This guideline addresses important clinical questions that arise in psoriasis management and care and […]

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Efficacy of a second IL-17 inhibitor in patients with psoriasis: a systematic review and meta-analysis.

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Multiple biologics for psoriasis exist and interleukin (IL)-17 inhibitors are among those with best efficacy. However, switching treatment is often required at some point and intraclass switch of IL-17 inhibitors […]

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Clinical Benefit of Baseline Imaging in Merkel Cell Carcinoma: Analysis of 584 Patients.

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Merkel cell carcinoma (MCC) guidelines derive from melanoma and do not recommend baseline cross-sectional imaging for most patients. However, MCC is more likely to have metastasized at diagnosis than melanoma.To […]

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Practical approaches for diagnosis and management of prurigo nodularis: US expert panel consensus.

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Prurigo nodularis (PN) is a chronic disease characterized by intensely pruritic, raised, nodular lesions. As there are currently no US Food and Drug Administration-approved therapies specifically for PN, management is […]

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Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma amongst chronic lymphocytic leukemia patients.

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The incidence of cutaneous squamous cell carcinoma (SCC) in chronic lymphocytic leukemia (CLL) patients is significantly higher compared to age- and sex- matched controls.To evaluate the association of factors associated […]

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The Arabic Urticaria Activity Score and Chronic Urticaria Quality of Life Questionnaire: validation and correlations.

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The international guideline for urticaria recommends the use of the Urticaria Activity Score 7 (UAS7) and the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) to assess patients with chronic spontaneous […]

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Review of Transition of Care Literature: Epidermolysis Bullosa, A Paradigm for Patients with Complex Dermatologic Conditions.

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Transition from pediatric to adult care is a critical component of healthcare for children with chronic needs. The characteristics of epidermolysis bullosa (EB) demand higher than average levels of provider […]

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Intraoperative dermoscopy features of subungual squamous cell carcinoma: a study of 53 cases.

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Subungual squamous cell carcinoma (SU-SCC) is the most common malignant tumor of the nail unit. Intraoperative nail dermoscopy has only been described for pigmented tumors, onychomatricoma and glomus tumors.Description of […]

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Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: a systematic review.

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Alopecia areata (AA) is an immune-mediated disease resulting in non-scarring hair loss. Systematic reviews on the psychosocial and psychiatric comorbidities, health-related quality of life, and interventions targeting psychosocial well-being are […]

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Comparing the efficacy and tolerability of biologic therapies in psoriasis: an updated network meta-analysis.

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The rapid expansion of psoriasis biologics has led to an urgent need to understand their relative efficacy and tolerability to better inform treatment decisions and specifically, to inform guideline development.We […]

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Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Study (PROCLIPI study).

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The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study is a prospective analysis of an international database and here we examine front-line treatments and quality-of-life in patients with newly diagnosed […]

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Paediatric morphoea: a holistic review. Part 1: epidemiology, aetiopathogenesis and clinical classification.

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Morphoea, also known as localized scleroderma, is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Paediatric-onset disease is not uncommon and is associated with frequent […]

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Reflectance confocal microscopy terminology glossary for melanocytic skin lesions: A systematic review.

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There is lack of uniformity in the reflectance confocal microscopy (RCM) terminology for melanocytic lesions.To review published RCM terms for melanocytic lesions and identify redundant, synonymous terms.Systematic review of original […]

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Paediatric morphoea: a holistic review. Part 2: diagnosis, measures of disease activity, management and natural history.

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Paediatric morphoea is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Defining optimum management strategies in paediatric morphoea remains an ongoing challenge, owing to the […]

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Pathophysiology, Clinical Presentation, and Treatment of Psoriasis: A Review.

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Approximately 125 million people worldwide have psoriasis. Patients with psoriasis experience substantial morbidity and increased rates of inflammatory arthritis, cardiometabolic diseases, and mental health disorders.Plaque psoriasis is the most common […]

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Assessing the incidence of skin and soft tissue infection in patients on biologics.

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Biologic agents may predispose patients to skin and soft tissue infections (SSTIs). Guidelines recommend discontinuing the agent pre-operatively; the true risk of infection is unclear.To assess the incidence of SSTIs […]

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The validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™): The development and reliability testing of a novel clinical outcome measurement instrument for the severity of atopic dermatitis.

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An Investigator Global Assessment (IGA) is recommended by health agencies for drug registration in atopic dermatitis (AD). Current IGA scales lack standardization.To develop an IGA scale, training module, and clinical […]

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A systematic review evaluating the efficacy and safety of a combination of ablative treatment and self administered treatment versus ablative treatment alone for external anogenital warts.

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External anogenital warts are proliferative lesions. Till now, there is no consensus on the standard treatment of external anogenital warts. The combination of ablative therapy and self-administered treatment has been […]

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Treatment of erythrodermic psoriasis with biologics: A systematic review.

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Biologic medications for plaque psoriasis have been used to treat erythrodermic psoriasis (EP). Since the guidelines for management of EP were published, new biologics have been approved for the treatment […]

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