Recommended core outcome instruments for health-related quality of life, long-term control and itch intensity in atopic eczema trials: results of the HOME VII consensus meeting.

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The Harmonising Outcome Measures for Eczema (HOME) initiative has established a core outcome set of domains for atopic eczema clinical trials. Previous consensus meetings have agreed upon preferred instruments for […]

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British Association of Dermatologists guidelines for the management of people with cutaneous squamous cell carcinoma 2020.

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The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of cutaneous squamous cell carcinoma (cSCC). The document aims to: offer an appraisal of all […]

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Incomplete surgical excision of keratinocyte skin cancers: a systematic review and meta-analysis.

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Keratinocyte or non-melanoma skin cancer (NMSC) is the commonest malignancy worldwide. Usual treatment is surgical excision. Current guidelines underestimate incomplete excision rates.We aimed to determine the risk of incomplete excision […]

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Thrombotic complications with interruption of direct oral anticoagulants in dermatologic surgery.

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Direct oral anticoagulants (DOACs) i.e. apixaban, rivaroxaban, and dabigatran are increasingly being utilized to provide prophylaxis and treatment for arterial and venous thromboembolism. While multiple procedural subspecialties have implemented guidelines […]

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Ulcerative versus non-ulcerative panniculitis: is it time for a novel clinical approach to panniculitis?

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Panniculitis, or inflammation of the fatty tissue, is an ongoing diagnostic challenge to both dermatologists and pathologists. The basis of the current panniculitis classification is histology, whether the inflammation is […]

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Occupational Dermatitis to Facial Personal Protective Equipment in Healthcare Workers: A Systematic Review.

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Prolonged wear of facial protective equipment can lead to occupational dermatoses.To identify important causes of occupational dermatoses from facial protective equipment.A systematic review following PRISMA guidelines was performed using PubMed […]

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Pain management in hidradenitis suppurativa and a proposed treatment algorithm.

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Pain contributes substantially to reduced quality of life in individuals living with hidradenitis suppurativa (HS). Although improved understanding of HS pathogenesis and treatment has resulted in improved evidence-based HS management […]

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The Alopecia Areata Consensus of Experts (ACE) Study PART II: Results of an International Expert Opinion on Diagnosis and Laboratory Evaluation for Alopecia Areata.

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We previously reported The Alopecia Areata Consensus of Experts (ACE) Study: Results of an International Expert Opinion on Treatments for Alopecia Areata (AA).To report the results of the ACE international […]

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The Alopecia Areata Consensus of Experts (ACE) Study PART II: Results of an International Expert Opinion on Diagnosis and Laboratory Evaluation for Alopecia Areata.

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We previously reported The Alopecia Areata Consensus of Experts (ACE) Study: Results of an International Expert Opinion on Treatments for Alopecia Areata (AA).To report the results of the ACE international […]

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Research priorities and identification of a health-service delivery model for psoriasis from the UK Psoriasis Priority Setting Partnership.

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Psoriasis impacts the health and psychosocial functioning of patients, conferring a significant economic burden on healthcare systems. There remain unmet needs in psoriasis care, which if addressed by research, could […]

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Diagnosis of Mycoplasma aetiology in Stevens-Johnson Syndrome / Toxic Epidermal Necrolysis.

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We were pleased that the first national guidelines for paediatric Stevens-Johnson Syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) were published in your journal last year1 . They highlighted the higher […]

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fJoint AAD-NPF Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity measures.

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Psoriasis is a chronic, inflammatory, multisystem disease which affects up to 3.2% of the U.S population. This guideline addresses important clinical questions that arise in psoriasis management and care and […]

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Efficacy of a second IL-17 inhibitor in patients with psoriasis: a systematic review and meta-analysis.

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Multiple biologics for psoriasis exist and interleukin (IL)-17 inhibitors are among those with best efficacy. However, switching treatment is often required at some point and intraclass switch of IL-17 inhibitors […]

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Clinical Benefit of Baseline Imaging in Merkel Cell Carcinoma: Analysis of 584 Patients.

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Merkel cell carcinoma (MCC) guidelines derive from melanoma and do not recommend baseline cross-sectional imaging for most patients. However, MCC is more likely to have metastasized at diagnosis than melanoma.To […]

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Practical approaches for diagnosis and management of prurigo nodularis: US expert panel consensus.

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Prurigo nodularis (PN) is a chronic disease characterized by intensely pruritic, raised, nodular lesions. As there are currently no US Food and Drug Administration-approved therapies specifically for PN, management is […]

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Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma amongst chronic lymphocytic leukemia patients.

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The incidence of cutaneous squamous cell carcinoma (SCC) in chronic lymphocytic leukemia (CLL) patients is significantly higher compared to age- and sex- matched controls.To evaluate the association of factors associated […]

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The Arabic Urticaria Activity Score and Chronic Urticaria Quality of Life Questionnaire: validation and correlations.

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The international guideline for urticaria recommends the use of the Urticaria Activity Score 7 (UAS7) and the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) to assess patients with chronic spontaneous […]

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Review of Transition of Care Literature: Epidermolysis Bullosa, A Paradigm for Patients with Complex Dermatologic Conditions.

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Transition from pediatric to adult care is a critical component of healthcare for children with chronic needs. The characteristics of epidermolysis bullosa (EB) demand higher than average levels of provider […]

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Intraoperative dermoscopy features of subungual squamous cell carcinoma: a study of 53 cases.

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Subungual squamous cell carcinoma (SU-SCC) is the most common malignant tumor of the nail unit. Intraoperative nail dermoscopy has only been described for pigmented tumors, onychomatricoma and glomus tumors.Description of […]

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Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: a systematic review.

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Alopecia areata (AA) is an immune-mediated disease resulting in non-scarring hair loss. Systematic reviews on the psychosocial and psychiatric comorbidities, health-related quality of life, and interventions targeting psychosocial well-being are […]

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Comparing the efficacy and tolerability of biologic therapies in psoriasis: an updated network meta-analysis.

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The rapid expansion of psoriasis biologics has led to an urgent need to understand their relative efficacy and tolerability to better inform treatment decisions and specifically, to inform guideline development.We […]

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Treatment of early-stage mycosis fungoides: results from the PROspective Cutaneous Lymphoma International Study (PROCLIPI study).

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The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study is a prospective analysis of an international database and here we examine front-line treatments and quality-of-life in patients with newly diagnosed […]

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Paediatric morphoea: a holistic review. Part 1: epidemiology, aetiopathogenesis and clinical classification.

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Morphoea, also known as localized scleroderma, is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Paediatric-onset disease is not uncommon and is associated with frequent […]

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Reflectance confocal microscopy terminology glossary for melanocytic skin lesions: A systematic review.

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There is lack of uniformity in the reflectance confocal microscopy (RCM) terminology for melanocytic lesions.To review published RCM terms for melanocytic lesions and identify redundant, synonymous terms.Systematic review of original […]

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Paediatric morphoea: a holistic review. Part 2: diagnosis, measures of disease activity, management and natural history.

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Paediatric morphoea is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Defining optimum management strategies in paediatric morphoea remains an ongoing challenge, owing to the […]

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