Paediatric morphoea: a holistic review. Part 2: diagnosis, measures of disease activity, management and natural history.

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Paediatric morphoea is a debilitating fibrosing disorder of uncertain aetiology, affecting the skin and subcutaneous tissues. Defining optimum management strategies in paediatric morphoea remains an ongoing challenge, owing to the […]

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Shorter survival and later stage at diagnosis among unmarried patients with cutaneous melanoma: a US national and tertiary care center study.

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Addressing risk factors of delayed melanoma detection minimizes disparities in outcome.Elucidate the significance of marital status in melanoma outcomes across anatomic sites.Retrospective cohort study of 73,558 patients from the Surveillance, […]

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A Retrospective Cohort Study of the Diagnostic Value of Different Subtypes of Atypical Pigment Network on Dermoscopy.

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Atypical network encompasses several patterns. Few studies assess the sensitivity, specificity, and positive and negative predictive values of network subtypes.We assessed the diagnostic value of atypical network subtypes and their […]

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A Phase IIb, Randomized Clinical Trial of Tapinarof Cream for the Treatment of Plaque Psoriasis: Secondary Efficacy and Patient-Reported Outcomes.

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Tapinarof cream is a topical therapeutic aryl hydrocarbon receptor modulating agent (TAMA) under investigation for treatment of psoriasis and atopic dermatitis.In a phase IIb, double-blind, vehicle-controlled study, adults with plaque […]

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Efficacy and safety of Jessner’s solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.

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Antibiotics and retinoids have been used for acne vulgaris for decades. Though effective, each has its own drawbacks. Chemical peels have been used for treatment of acne vulgaris with inadequate […]

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The Infection Rate of Intralesional Triamcinolone and The Safety of Compounding in Dermatology for Intradermal and Subcutaneous Injection: A Retrospective Chart Review.

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Intralesional injection of sterile medications remains a mainstay in dermatology, enabling a tailored, low-cost, in-office therapy. Following the 2012 United States outbreak of fungal meningitis from contaminated intrathecally administered corticosteroids, […]

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The role of reflectance confocal microscopy in differentiating melanoma in situ from dysplastic nevi with severe atypia: a cross-sectional study.

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Melanoma in situ (MMIS) and dysplastic nevi with severe atypia (DNSA) present overlapping histopathological features. Reflectance Confocal Microscopy (RCM) findings can be integrated with the dermatopathology report to improve differentiation […]

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Adoptive cell transfer (ACT) of autologous tumor-infiltrating lymphocytes (TILs) to treat malignant melanoma: the dawn of a chimeric antigen receptor T (CAR-T) cell therapy from autologous donor.

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Tumor-infiltrating lymphocytes (TILs) are B, T-helper, and T-cytotoxic lymphocytes migrated from the blood or lymph stream toward a tumor with the aim to infiltrate and destroy it. They can be […]

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