Clinico-epidemiological profile of lichen scrofulosorum: a 22-year, single-center, retrospective study.

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Lichen scrofulosorum (LS) represents immunologic reaction to the Mycobacterium tuberculosis antigen and presents with subtle, asymptomatic, grouped follicular papules over the trunk and shows good therapeutic response to antitubercular drugs.To […]

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The in vitro effect of nanoliposomal amphotericin B against two clinically important dermatophytes.

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The present study aimed to investigate the antifungal activity of amphotericin B-loaded nanoliposomes against Trichophyton interdigitale and Trichophyton rubrum. Moreover, it was attempted to assess the obtained resistance in vitro.In […]

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Is it possible to repigment iatrogenic and traumatic hypochromic lesions? A case series using the MMP® drug delivery technique with 5-fluorouracil and bleomycin.

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We present the results of 11 patients with hypochromic lesions treated with antifibrotic agents delivered through the MMP® technique.Eleven patients with hypochromic lesions because of external injuries were treated at […]

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International multicentre observational study to assess the efficacy and safety of a 0.5 mg/kg/day starting dose of oral corticosteroids to treat bullous pemphigoid.

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European guidelines propose a 0.5 mg/kg/day dose of oral prednisone as initial treatment of bullous pemphigoid (BP). We assessed the safety and efficacy of this regimen depending on BP extent, […]

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British Association of Dermatologists guidelines for the management of people with cutaneous lupus erythematosus (CLE) 2021.

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The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of cutaneous lupus erythematosus (CLE) in the presence or absence of systemic lupus erythematosus (SLE) […]

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Pityriasis lichenoides: a clinical and pathological case series of 49 patients with an emphasis on follow-up.

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The classification of pityriasis lichenoides (PL) into pityriasis lichenoides et varioliformis acuta (PLEVA), PL chronica (PLC) or febrile ulceronecrotic Mucha-Habermann disease (FUMHD) mixes clinical and chronological features. In this retrospective […]

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An analysis of qualitative responses from a UK survey of the psychosocial wellbeing of people with skin conditions and their experiences of accessing psychological support.

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Skin conditions have a large emotional, psychological and psychiatric impact on the individual. The ‘All-Party Parliamentary Group on Skin’ (APPGS) commissioned a qualitative survey in order to further explore this […]

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Long-term efficacy and safety of risankizumab for the treatment of moderate-to-severe plaque psoriasis: interim analysis of the LIMMitless open-label extension trial beyond 3 years of follow-up.

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Psoriasis is a chronic inflammatory skin disease requiring prolonged treatment. New biologic therapies require long-term evaluation to assess durability of their efficacy and safety profile over time.To evaluate long-term efficacy […]

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Late-onset adverse events under anti-PD1 therapy in melanoma patients: an observational study from MELBASE, a nationwide prospective cohort.

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The purpose was to evaluate late-onset AEs in melanoma patients treated with anti-PD1 administered at least 2 years in a real-life setting. Patients were screened from MelBase (NCT02828202), a French […]

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Tumor invasion in the hyponychium is associated with distant metastasis and poor prognosis in subungual melanoma: A histological landscape of 44 cases.

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Subungual melanoma (SUM) has a poor prognosis due to delayed diagnosis. The progression, consensus on surgical treatment, correlation with clinical outcomes remains unclear.We aimed to identify the pattern of dermal […]

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Prevalence of Depression among Children, Adolescents, and Adults with Hidradenitis Suppurativa.

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Information on prevalence of depression among children, adolescents and adults with hidradenitis suppurativa (HS) is limited.To compare prevalence of depression in HS patients with that of controls.Cross-sectional analysis of 38,140 […]

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Multicentric EORTC retrospective study shows efficacy of Brentuximab Vedotin in Μycosis Fungoides and Sezary Syndrome patients with variable CD30 positivity.

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Brentuximab Vedotin (BV) was approved as therapy for Mycosis Fungoides (MF) based on ALCANZA trial. Since then few real-life data are available.The aim of this study was to evaluate efficacy […]

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Alcohol abuse associated with poor response to systemic therapies for psoriasis: findings from a prospective multicentre cohort study.

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Factors that might influence response to systemic treatment for moderate-to-severe psoriasis are varied, and generally, are poorly understood, aside from high body weight, suggesting that other unidentified factors may be […]

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Development and preliminary validation of the patient-reported Chronic Itch Burden Scale, assessing health-related quality of life in chronic pruritus.

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Chronic pruritus (CP) significantly affects patients’ health-related quality of life (HRQoL). Very few self-reported HRQoL questionnaires exploring CP were developed according to international guidelines thus limiting their use in pre-authorization […]

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Delgocitinib ointment in pediatric patients with atopic dermatitis: a phase 3, randomized, double-blind, vehicle-controlled study and a subsequent open-label, long-term study.

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Delgocitinib 0.5% ointment, a topical JAK inhibitor, has been approved for adult patients with atopic dermatitis (AD) in Japan.To evaluate the efficacy and safety of delgocitinib ointment in pediatric patients […]

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