The care of breast cancer patients is important to dermatologists. Breast cancer’s initial presentation, clinical progression, and its associated treatments can result in a variety of cutaneous complications. Dermatologists may […]» Read more
The role of dermoscopy in diagnostics of dermatological conditions of the eyelid, eyelashes, and conjunctiva – a literature review.
The role of dermoscopy in dermatology is constantly evolving. Relatively little is known about its application in diagnosis of dermatological conditions of the eyelid, eyelashes, and conjunctiva. The aim of […]» Read more
A novel c.916C>A EDA gene pathogenic variant in a boy with X-Linked Hypohidrotic Ectodermal Dysplasia.
A 17-month old boy was referred to the genetic clinic in view of anodontia, hypohidrosis, scalp hypotrichosis, atrichia of the eyelashes, xerotic skin and a short columella. A diagnosis of […]» Read more
Next steps in dermatology training: choosing to enter higher specialty training and the transition from trainee to consultant dermatologist.
Junior doctors are required to make career decisions at an early stage in their postgraduate training. Trainees also feel inadequately prepared for the transition to consultant roles.An online questionnaire was […]» Read more
Silicone adhesive multilayer foam dressings as adjuvant prophylactic therapy to prevent hospital-acquired pressure ulcers: a pragmatic non-commercial multicentre randomised open label parallel group medical device trial.
Silicone adhesive multilayer foam dressings are used as adjuvant therapy to prevent hospital-acquired pressure ulcers (PUs).Determine if silicone foam dressings in addition to standard prevention reduce PU incidence category 2 […]» Read more
Incidence of acute complications of herpes zoster among immunocompetent adults in England: a matched cohort study using routine health data.
Herpes zoster can cause rare but serious complications; the frequency of these complications has not been well-described.We aimed to quantify the risks of acute non-postherpetic neuralgia (PHN) zoster complications, to […]» Read more
Rosacea is a chronic inflammatory condition that affects the skin and the eyes. The pathogenesis of rosacea is complex and includes the interaction between genetic and environmental factors, dysregulation of […]» Read more
In 2017, health and social care organisations contributed 6.3% of carbon emissions in England. Efforts to reduce the environmental footprint of the NHS have been broadly focussed on reducing demand, […]» Read more
A 7-year-old Chinese girl presented with a 5-year history of multiple skin-colored papules on the nasal dorsum, nasolabial folds and eyelids, which increased in size and number with age. On […]» Read more
We have observed an increasing number of patients referred to the Scottish Photobiology Service (SPS), who are diagnosed with Actinic Folliculitis (AF) and have positive phototesting. Treatment options for AF […]» Read more
Use of Hydrochlorothiazide and Risk of Non-melanoma Skin Cancer in Koreans: A Retrospective Cohort Study Using Administrative Healthcare Data.
The incidence of skin cancer is increasing because of the aging population and ultraviolet exposure, and previous studies revealed that long-term use of hydrochlorothiazide (HCTZ), one of the antihypertensive agents, […]» Read more
Pediatric Allergic Contact Dermatitis. Part II. Patch Testing Series, Procedure, and Unique Scenarios.
Patch testing is the gold standard for diagnosing allergic contact dermatitis. Causative allergens differ between children and adults, necessitating the development of pediatric-specific patch test series. The Pediatric Baseline Series […]» Read more
Pediatric Allergic Contact Dermatitis. Part I. Clinical Features and Common Contact Allergens in Children.
Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations […]» Read more
Skin sensitisation to fragrance hydroperoxides: interplay between dendritic cells, keratinocytes and free radicals.
Skin sensitisation to hydroperoxides (R-OOHs) of the commonly used fragrance terpenes limonene, linalool and citronellol is frequently reported. R-OOHs are believed to initiate the process leading to sensitisation and allergic […]» Read more
Pemphigus vulgaris (PV) is a life-threatening mucocutaneous autoimmune blistering disease. We previously showed that genetic variants within the ST18 gene promoter area confer a 6-fold increase in the propensity to […]» Read more
Evaluation of Dermatological Life Quality Index, Sexual Dysfunction, and Other Psychiatric Diseases in Patients Diagnosed with Vitiligo with and without Genital Involvement.
Because skin lesions affect self-image, vitiligo affects an individual’s emotional and psychological well-being, sexual life, and relationships with other people. The literature contains a limited number of studies regarding the […]» Read more
The use of direct oral challenge to confirm allergies to penicillin class antibiotics in Danish children.
A high number of children are referred to pediatric departments with a suspected allergic reaction to antibiotics. The prevalence of true allergy is considered to be significantly lower than shown […]» Read more
Discoid lupus erythematosus (DLE) is a common manifestation of lupus erythematosus. Hydroxychloroquine is commonly used in the treatment of lupus erythematosus. The present study aims to report hallucinations induced by […]» Read more
Electronic learning for Healthcare (e-LfH) e-Dermatology modules as a key educational tool for trainees during the COVID-19 pandemic: a regional experience.
The COVID-19 pandemic has dramatically impacted clinical practice due to staff redeployment, reduced face-to-face patient contact and the temporary closure of routine services1 . Consequently, this has had a negative […]» Read more
Hand-foot syndrome (HFS) is a common systemic skin toxicity syndrome caused by chemotherapy agents. However, there is no uniform clinical treatment for HFS. It is reported that pyridoxine (vitamin B6) […]» Read more
Pachyonychia congenita (PC) is a rare autosomal dominant disorder featuring palmoplantar keratoderma, nail dystrophy, oral leukokeratosis, pilosebaceous cysts and natal teeth. PC results from dominant mutations in one of five […]» Read more
Clinical characteristics and histopathological changes of morphea: A single-center, retrospective study of 137 patients.
The clinicopathologic correlations and prognostic risk factors for refractory disease in morphea (localized scleroderma) are poorly described.To investigate the association between clinical characteristics and histopathological features of morphea and identify […]» Read more
Recommended core outcome instruments for health-related quality of life, long-term control and itch intensity in atopic eczema trials: results of the HOME VII consensus meeting.
The Harmonising Outcome Measures for Eczema (HOME) initiative has established a core outcome set of domains for atopic eczema clinical trials. Previous consensus meetings have agreed upon preferred instruments for […]» Read more
The current COVID-19 pandemic is caused by the SARS-CoV-2 coronavirus. The initial recognized symptoms were respiratory, sometimes culminating in severe respiratory distress requiring ventilation, and causing death in a percentage […]» Read more
Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial: a critical appraisal.
Vitiligo is an acquired condition which presents as cutaneous depigmentation. There is no licensed treatment for the re-pigmentation of vitiligo lesions, however, several therapies are used routinely and have been […]» Read more
Coronavirus disease 2019 (COVID-19) is a systemic multi-organ viral illness. Previous studies have found that many patients had a procoagulant state and/or severe hypoxemia with relatively well-preserved lung mechanics. Mechanisms […]» Read more
Lessons From the First Wave of the Pandemic: Skin Features of COVID-19 can be Divided Into Inflammatory and Vascular Patterns.
This review examines the clinical, morphological, and systemic factors related to coronavirus disease 2019 (COVID-19) cutaneous manifestations. The EMBASE, Medline, and Pubmed Central databases were searched from February 1, 2020 […]» Read more
Research impact describes whether and how research results in wider benefits to society beyond academic publication. Little is known about translation of clinical trial research into dermatological practice .We scoped […]» Read more
Coronavirus disease 2019 (COVID-19) emerged in Thailand in January 2020. Thailand was the first to report a confirmed case outside China. Cutaneous eruption in COVID-19 has been reported since the […]» Read more
The role of neuroimaging in neurocutaneous disorders is an evolving field. Research can be inconsistent and inconclusive, leading to divergent practice for some disorders. This study provides an overview of […]» Read more