Lithium, widely used in treating bipolar disorder, also exhibits antiviral activity.1 Lithium’s antiviral effects may extend to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-19), which causes coronavirus disease 2019 (COVID-19). […]» Read more
Real Asymptomatic SARS-CoV-2 Infection Might Be Rare: Importance of Careful Interviews and Follow-up.
There is limited information on the clinical characteristics of patients with coronavirus disease 2019 (COVID-19) who are asymptomatic or have mild symptoms.We performed a retrospective case series of patients with […]» Read more
We aimed to compare COVID-19-specific and all-cause mortality rates among natives and migrants in Italy and to investigate the clinical characteristics of individuals dying with COVID-19 by native/migrant status. The […]» Read more
Severe acute respiratory syndrome coronavirus-2 causes the clinical syndrome of coronavirus disease of 2019 (COVID-19) which has become a global pandemic resulting in significant morbidity and mortality. While the virus […]» Read more
The roles of inflammation and hypercoagulation in predicting outcomes of coronavirus disease 2019 (COVID-19) are unclear.Adult patients diagnosed with COVID-19 from 28 January 2020 to 4 March 2020 in Tongji […]» Read more
Ethnic differences in alpha-1 antitrypsin deficiency allele frequencies may partially explain national differences in COVID-19 fatality rates.
Infection rates, severity, and fatalities due to COVID-19, the pandemic mediated by SARS-CoV-2, vary greatly between countries. With few exceptions, these are lower in East and Southeast Asian and Sub-Saharan […]» Read more
Assessment of the efficacy and safety of Ribavirin in treatment of coronavirus-related pneumonia (SARS, MERS and COVID-19): A protocol for systematic review and meta-analysis.
The new coronavirus-related pneumonia is causing a global pandemic without specific antiviral drug. Ribavirin has activity against extensive RNA and DNA viruses. We plan to systematically review the use of […]» Read more
Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: A nationwide cohort study.
There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease […]» Read more
COVID19-world: a shiny application to perform comprehensive country-specific data visualization for SARS-CoV-2 epidemic.
Data analysis and visualization is an essential tool for exploring and communicating findings in medical research, especially in epidemiological surveillance.Data on COVID-19 diagnosed cases and mortality, from January 1st, 2020, […]» Read more
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis […]» Read more
The Coronavirus disease 2019 (COVID-19) pandemic has been especially devastating among nursing home residents, with both the health circumstances of individual residents as well as communal living settings contributing to […]» Read more
The COVID-19 pandemic has substantially impacted the conduct of clinical trials. While initially preparing for a period of time, where it would likely be impossible to supervise trials in the […]» Read more
Children and youth infected with SARS-CoV-2 have milder disease than do adults and, even among those with the recently described multi-system inflammatory syndrome (MIS-C), mortality is rare. The reasons for […]» Read more
The first cases of coronavirus disease 2019 (COVID-19) were reported in December 2019 and the outbreak of SARS-CoV-2 was declared a pandemic in March 2020 by the World Health Organization. […]» Read more
Perspective on fibrinolytic therapy in COVID-19: the potential of inhalation therapy against suppressed-fibrinolytic-type DIC.
A high rate of thrombotic complications, such as pulmonary embolism, has been linked to mortality in COVID-19, and appropriate treatment of thrombosis is important for lifesaving. Although heparin is frequently […]» Read more
Do free radical NETwork and oxidative stress disparities in African Americans enhance their vulnerability to SARS-CoV-2 infection and COVID-19 severity?
This review focuses on the hypothetical mechanisms for enhanced vulnerability of African Americans to SARS-CoV-2 infection, COVID-19 severity, and increased deaths. A disproportionately higher number of African Americans are afflicted […]» Read more
Does Asthma Increase the Mortality of Patients with COVID-19?: A Systematic Review and Meta-Analysis.
The purpose of this systematic review and meta-analysis was to explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma. The […]» Read more
For a long time, most of the infectious diseases seemed to have become under control. In particular, vaccinations have contributed to this development. In recent years newly occurring bacterial infections caused […]» Read more
SARS-CoV-2, the causal agent of COVID-19, has become a major public health issue. The severe morbidity and mortality associated with SARS-CoV-2 necessitate the development of effective vaccines to prevent epidemics. […]» Read more
The coronavirus disease 2019 mortality rate among Black adults in the U.S. is double that of other racial and ethnic groups. The current pandemic is re-illuminating health inequities that are […]» Read more
Considering the relevance of the Quality of life (QoL) and the consequences of the 2019 new coronavirus disease (COVID-19) due to the social distancing, this systematic review aimed to summarize […]» Read more
Core Elements of a National COVID-19 Strategy: Lessons Learned from the US National HIV/AIDS Strategy.
COVID-19 has caused devastating health consequences and social inequities globally and in the United States. Unfortunately, the US has not developed a comprehensive National COVID-19 Strategy. In this editorial, we […]» Read more
Coronavirus Disease 2019 (COVID-19) has become a pandemic outbreak. Risk stratification at hospital admission is of vital importance for medical decision making and resource allocation. There is no sophisticated tool […]» Read more
The Severe Acute Respiratory Syndrome-related Coronavirus-2 (SARS-CoV2) pandemic has sparked controversy regarding the use of certain routine and investigational pharmacologic interventions during pregnancy and the postpartum period. In this review, […]» Read more
With the emergence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the whole world is suffering from atypical pneumonia which resulted in more than 559,047 deaths worldwide. In this […]» Read more
We believe that forensic medicine should play a significant role in the COVID-19 pandemic. Forensic pathologists should ask and answer various questions through autopsy cases during the COVID-19 period, thus […]» Read more
Characterization of Patients with COVID-19 Admitted to a Community Hospital of East Harlem in New York City.
Background New York City was the epicenter for the coronavirus disease 2019 (COVID-19) in the United States. Accordingly, the aim of this study was to characterize the population of patients […]» Read more
Maternal deaths in Brazil from severe COVID-19 respiratory disease: Time for a global commitment to ending health disparities.
In this issue, Takemoto M. et al. report on 124 maternal deaths among individuals with SARS-CoV-2 attributable acute respiratory distress syndrome (ARDS) in Brazil leveraging an ARDS surveillance system established […]» Read more
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is associated with stroke. The role of sex on stroke outcome has not been investigated. To objective of this paper is to […]» Read more
SARS-CoV-2 is a novel betacoronavirus which infects the lower respiratory tract and can cause coronavirus disease 2019 (COVID-19), a complex respiratory distress syndrome. Epidemiological data show that COVID-19 has a rising […]» Read more