Axial flow ventricular assist devices in cardiogenic shock complicating acute myocardial infarction.

Bookmark this %label%

Cardiogenic shock (CS) remains the leading cause of death in patients hospitalised with acute myocardial infarction with mortality as high as 40%-50% prior to hospital discharge. The failure of inotropic […]

» Read more

Intensive low-density lipoprotein cholesterol lowering in cardiovascular disease prevention: opportunities and challenges.

Bookmark this %label%

Elevated levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased risk of coronary heart disease and stroke. Guidelines for the management of dyslipidaemia from the European Society of Cardiology […]

» Read more

Association of the combined effects of air pollution and changes in physical activity with cardiovascular disease in young adults.

Bookmark this %label%

Little is known about the trade-off between the health benefits of physical activity (PA) and the potential harmful effects of increased exposure to air pollution during outdoor PA. We examined […]

» Read more

Stress-associated neurobiological activity associates with the risk for and timing of subsequent Takotsubo syndrome.

Bookmark this %label%

Activity in the amygdala, a brain centre involved in the perception of and response to stressors, associates with: (i) heightened sympathetic nervous system and inflammatory output and (ii) risk of […]

» Read more

Usefulness of Antiplatelet Therapy After Transcatheter Aortic Valve Implantation.

Bookmark this %label%

The rationale for dual antiplatelet therapy (DAPT) after transcatheter aortic valve implantation (TAVI) is to facilitate endothelialization of metallic struts of the transcatheter heart valve (THV) and to prevent thrombosis […]

» Read more

Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.

Bookmark this %label%

Inflammation plays an important role in cardiovascular disease (CVD) development. The NOD-like receptor protein-3 (NLRP3) inflammasome contributes to the development of atherosclerosis in animal models. Components of the NLRP3 inflammasome […]

» Read more

Influenza vaccination: a ‘shot’ at INVESTing in cardiovascular health.

Bookmark this %label%

The link between viral respiratory infection and non-pulmonary organ-specific injury, including cardiac injury, has become increasingly appreciated during the current coronavirus disease 2019 (COVID-19) pandemic. Even prior to the pandemic, […]

» Read more

Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.

Bookmark this %label%

Atrial fibrillation (AF) is the most common heart rhythm disturbance, continues to increase in incidence, and results in significant morbidity and mortality. The marine omega-3 fatty acids, eicosapentaenoic acid (EPA) […]

» Read more

Aspirin for Primary Prevention of Cardiovascular Disease in the 21st Century: A Review of the Evidence.

Bookmark this %label%

Aspirin (ASA) is the most commonly prescribed antiplatelet agent. Although the evidence for efficacy of aspirin for secondary prevention of ischemic events in patients with established cardiovascular disease is strong, […]

» Read more

Evolution of Clinical Thinking and Practice Regarding Aspirin: What Has Changed and Why?

Bookmark this %label%

Aspirin (ASA) is the original antiplatelet agent. Its routine use, long unquestioned for both primary and secondary prevention in cardiovascular disease, is under increasing scrutiny as the risk:benefit balance for […]

» Read more

Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the BIOSIGNAL study.

Bookmark this %label%

Lipoprotein(a) [Lp(a)] is a recognized causal risk factor for atherosclerotic cardiovascular disease but its role for acute ischaemic stroke (AIS) is controversial. In this study, we evaluated the association of […]

» Read more

A cohort study and meta-analysis of isolated diastolic hypertension: searching for a threshold to guide treatment.

Bookmark this %label%

Whether isolated diastolic hypertension (IDH), as defined by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline, is associated with cardiovascular disease (CVD) has been disputed. We aimed […]

» Read more

Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.

Bookmark this %label%

The American College of Cardiology / American Heart Association pooled cohort equations tool (ASCVD-PCE) is currently recommended to assess 10-year risk for atherosclerotic cardiovascular disease (ASCVD). ASCVD-PCE does not currently […]

» Read more

Thoracic Aortic Calcium For The Prediction Of Stroke Mortality (From The Coronary Artery Calcium Consortium).

Bookmark this %label%

Thoracic aortic calcium(TAC) is an important marker of extra-coronary atherosclerosis with established predictive value for all-cause mortality. We sought to explore the predictive value of TAC for stroke mortality, independent […]

» Read more

All-cause mortality and location of death in patients with established cardiovascular disease before, during, and after the COVID-19 lockdown: a Danish Nationwide Cohort Study.

Bookmark this %label%

On 13 March 2020, the Danish authorities imposed extensive nationwide lockdown measures to prevent the spread of the coronavirus disease 2019 (COVID-19) and reallocated limited healthcare resources. We investigated mortality […]

» Read more

Metabolic phenotyping and cardiovascular disease: an overview of evidence from epidemiological settings.

Bookmark this %label%

Metabolomics, the comprehensive measurement of low-molecular-weight molecules in biological fluids used for metabolic phenotyping, has emerged as a promising tool to better understand pathways underlying cardiovascular disease (CVD) and to […]

» Read more

Recreational substance use among patients with premature atherosclerotic cardiovascular disease.

Bookmark this %label%

Despite an upsurge in the incidence of atherosclerotic cardiovascular diseases (ASCVD) among young adults, the attributable risk of recreational substance use among young patients has been incompletely evaluated. We evaluated […]

» Read more

Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo.

Bookmark this %label%

The rapid endothelialization of bare metal stents (BMS) is counterbalanced by inflammation-induced neointimal growth. Drug-eluting stents (DES) prevent leukocyte activation but impair endothelialization, delaying effective device integration into arterial walls. […]

» Read more

Chronic kidney disease detection, staging and treatment in cardiovascular disease prevention.

Bookmark this %label%

Globally, nearly 10% of the population has chronic kidney disease (CKD), defined as a glomerular filtration rate less than 60 mL/min/1.73 m2 and/or a urinary albumin to creatinine ratio greater than 30 mg/g […]

» Read more

Influence of sex and phenotype on cardiac outcomes in patients with Fabry disease.

Bookmark this %label%

This study describes the influence of sex and disease phenotype on the occurrence of cardiac events in Fabry disease (FD).Cardiac events from birth to last visit (median age 50 years) […]

» Read more
1 2 3 15