ASPECTS-based net water uptake as an imaging biomarker for lesion age in acute ischemic stroke.
We assessed the value of computed tomography (CT) and automated Alberta Stroke Program Early CT Score (ASPECTS) with net water uptake (NWU) to predict stroke onset time.Two-hundred forty stroke patients with anterior circulation large-vessel occlusion were included. CT-ASPECTS-NWU values were calculated by comparing the mean Hounsfield units of affected ASPECTS regions with unaffected contralateral regions. The correlation between ASPECTS-NWU and stroke onset to CT time was assessed. ASPECTS-NWU predictive values were calculated to identify a stroke onset to CT time of within 4.5/6 h.A correlation existed between stroke onset to CT time and ASPECTS-NWU (r = 0.65, p
Authors: XiaoQing Cheng, Hang Wu, JiaQian Shi, Zheng Dong, Jia Liu, ChangSheng Zhou, QuanHui Liu, XiaoQin Su, Zhao Shi, YingLe Li, LuLu Xiao, WuSheng Zhu, GuangMing Lu