Latest Clinical Articles

A selection of the latest clinical articles from leading peer-reviewed medical journals. You can tailor the feed by selecting your specialty / sub-specialty in the menu above.

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• Vulnerability to psychological stress-induced anorexia in female mice depends on blockade of ghrelin signal in nucleus tractus solitarius.6th August 2020
  Women are characterized by a higher incidence of eating disorders than men. We aimed to investigate whether the effects of ghrelin on feeding are essentially affected by sex and stress and to elucidate the biological […]
• A sharp increase in the number of COVID-19 cases and case fatality rates after lifting the lockdown in Kurdistan region of Iraq.6th August 2020
  With the appearance of first cases of Coronavirus disease (COVID-19), strict control measures were implemented in the Kurdistan Region of Iraq to combat the infection. These measures included the closure of schools and universities, the […]
• Combined Prophylactic and Therapeutic Use Maximizes Hydroxychloroquine Anti-SARS-CoV-2 Effects in vitro.6th August 2020
  While the SARS-CoV-2 pandemic is heavily hitting the world, it is of extreme importance that significant in vitro observations guide the quick set up of clinical trials. In this study, we evidence that the anti-SARS-CoV2 […]
• Rethinking ‘essential’ and ‘nonessential’: the developmental paediatrician’s COVID-19 response.6th August 2020
  While terms such as ‘essential’ and ‘nonessential’ used amidst the COVID-19 pandemic may serve a practical purpose, they also pose a risk of obstructing our view of the harmful indirect health consequences of this crisis. […]
• Dynamic interplay between social distancing duration and intensity in reducing COVID-19 US hospitalizations: A “law of diminishing returns”.6th August 2020
  We uncover and highlight the importance of social distancing duration and intensity in lowering hospitalization demand-to-supply during the coronavirus disease 2019 (COVID-19) epidemic in the USA. We have developed an epidemic progression model involving the […]
• Objective Olfactory Findings in Hospitalized Severe COVID-19 Patients.6th August 2020
  We investigate the prevalence of the self-reported and objective sudden loss of smell (SLS) in patients with severe coronavirus disease 2019 (COVID-19).Severe COVID-19 patients with self-reported SLS were recruited at hospitalization discharge. Epidemiological and clinical […]
• Mathematical models and deep learning for predicting the number of individuals reported to be infected with SARS-CoV-2.6th August 2020
  We introduce a novel methodology for predicting the time evolution of the number of individuals in a given country reported to be infected with SARS-CoV-2. This methodology, which is based on the synergy of explicit […]
• Comparing eating behaviours, and symptoms of depression and anxiety between Spain and Greece during the COVID-19 outbreak: Cross-sectional analysis of two different confinement strategies.6th August 2020
  We compared eating behaviours, and depressive and anxiety symptoms in two countries with different confinement strictness strategies and different levels of COVID-19 pandemic.A web-based cross-sectional survey was administered during and shortly after the COVID-19 related […]
• Feasibility of Transcatheter Closure of Secundum Atrial Septal Defect in Low Weight Infants Under 2-Year-Old from a 3-year Retrospective Cohort Study.6th August 2020
  We aimed to evaluate the feasibility of interventional treatment of atrial septal defect (ASD) in low weight infants under 2-year-old. Seven hundred and ninety-three secundum ASD patients were divided into 2 groups: 665 were above […]
• Prevention of Venous Thromboembolism in 2020 and Beyond.6th August 2020
  Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the […]
• In-Hospital Outcomes of Left Ventricular Assist Device Implantation and Concomitant Valvular Surgery.6th August 2020
  Valvular heart disease is common among left ventricular assist device (LVAD) recipients. However, its management at the time of LVAD implantation remains controversial. Patients who underwent LVAD implantation and concomitant aortic (AVR), mitral (MVR), or […]
• Prevalence and Mortality of COVID-19 Patients With Gastrointestinal Symptoms: A Systematic Review and Meta-analysis.6th August 2020
  To perform a systematic review and meta-analysis evaluating the prevalence of gastrointestinal (GI) symptoms and mortality in patients with coronavirus disease 2019 (COVID-19) diagnosed.A systematic search of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, […]
• Psychological Distress and Its Correlates Among COVID-19 Survivors During Early Convalescence Across Age Groups.6th August 2020
  To examine the psychological distress and the associated predictor factors of the 2019 corona-virus disease (COVID-19) on survivors in the early convalescence in Shenzhen.A survey questionnaire consisting of post-traumatic stress disorder self-rating scale (PTSD-SS), self-rating […]
• Psychophysical evaluation of chemosensory functions 5 weeks after olfactory loss due to COVID-19: a prospective cohort study on 72 patients.6th August 2020
  To evaluate the evolution of chemosensation via extended psychophysical testing in patients who suffered from sudden chemosensory loss due to coronavirus disease 2019 (COVID-19). Additionally, this study sought to determine whether odor threshold testing provided […]
• [Perinatal COVID-19 in Latin America].6th August 2020
  To evaluate and report the clinical characteristics and outcomes of SARS-CoV-2 infection in pregnant women and newborns in Latin America.Descriptive study based on the prospective report of the units of the Ibero-American Society of Neonatology […]
• Smell and Taste Dysfunction in Patients With COVID-19: A Systematic Review and Meta-analysis.6th August 2020
  To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19).A systematic review was conducted by searching MEDLINE, EMBASE, and the preprint server MedRxiv from their inception […]
• A sialidosis type I cohort and a quantitative approach to multimodal ophthalmic imaging of the macular cherry-red spot.6th August 2020
  To describe the ophthalmologic findings on the largest cohort of patients with sialidosis type I due to deficiency of the lysosomal sialidase, neuraminidase 1 (NEU1) and to introduce a quantitative neuroretinal image analysis approach to […]
• Changes of Physical Activity and Ultra-Processed Food Consumption in Adolescents from Different Countries during Covid-19 Pandemic: An Observational Study.6th August 2020
  to describe physical activity and ultra-processed foods consumption, their changes and sociodemographic predictors among adolescents from countries in Europe (Italy and Spain) and Latin America (Brazil, Chile, and Colombia) during the SARS-CoV-2-pandemic period.Cross-sectional study via […]
• A Rapid, Simple, Inexpensive, and Mobile Colorimetric Assay COVID-19-LAMP for Mass On-Site Screening of COVID-19.6th August 2020
  To control the COVID-19 pandemic and prevent its resurgence in areas preparing for a return of economic activities, a method for a rapid, simple, and inexpensive point-of-care diagnosis and mass screening is urgently needed. We […]
• Sex Differences in Case Fatality Rate of COVID-19: Insights From a Multinational Registry.6th August 2020
  To confirm whether a relationship exists between male sex and coronavirus disease 2019 (COVID-19) mortality and whether this relationship is age dependent.We queried the COVID-19 Research Network, a multinational database using the TriNetX network, to […]
• Correlation between COVID-19 Morbidity and Mortality Rates in Japan and Local Population Density, Temperature, and Absolute Humidity.6th August 2020
  This study analyzed the morbidity and mortality rates of the coronavirus disease (COVID-19) pandemic in different prefectures of Japan. Under the constraint that daily maximum confirmed deaths and daily maximum cases should exceed 4 and […]
• Coronavirus-Related Health Literacy: A Cross-Sectional Study in Adults during the COVID-19 Infodemic in Germany.6th August 2020
  There is an “infodemic” associated with the COVID-19 pandemic-an overabundance of valid and invalid information. Health literacy is the ability to access, understand, appraise, and apply health information, making it crucial for navigating coronavirus and […]
• Reprocessing filtering facepiece respirators in primary care using medical autoclave: prospective, bench-to-bedside, single-centre study.6th August 2020
  There are widespread shortages of personal protective equipment as a result of the COVID-19 pandemic. Reprocessing filtering facepiece particle (FFP)-type respirators may provide an alternative solution in keeping healthcare professionals safe.Prospective, bench-to-bedside.A primary care-based study […]
• Asthma and COVID-19: What do we know?6th August 2020
  There are limited data about the coexistence of asthma and the Coronavirus disease-2019 (COVID-19). The COVID-19 pandemic is a new disease for the whole world. In this study, we aimed to examine the published case […]
• COVID-19 pandemic: Clinical management protocols for cardiac disease patients at teaching institute in Western Rajasthan.6th August 2020
  The world is facing the new pandemic COVID-19 caused by a novel coronavirus SARS-CoV-2. The demography and socio-economic condition are highly varied in different parts of the world. India also has braced itself to fight […]
• Predictive modeling by deep learning, virtual screening and molecular dynamics study of natural compounds against SARS-CoV-2 main protease.6th August 2020
  The whole world is facing a great challenging time due to Coronavirus disease (COVID-19) caused by SARS-CoV-2. Globally, more than 14.6 M people have been diagnosed and more than 595 K deaths are reported. Currently, no effective […]
• The Potential Vaccine Component for COVID-19: A Comprehensive Review of Global Vaccine Development Efforts.6th August 2020
  The whole world is concerned about the pandemic of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), due to fatality of this condition. This has become a public health emergency of […]
• Preliminary Study of Sars-Cov-2 Occurrence in Wastewater in the Czech Republic.6th August 2020
  The virus SARS-CoV-2, which has caused the recent COVID-19 pandemic, may be present in the stools of COVID-19 patients. Therefore, we aimed to detect SARS-CoV-2 in wastewater for surveillance of SARS-CoV-2 in the population. Samples […]
• Risk of COVID-19 due to Shortage of Personal Protective Equipment.6th August 2020
  The supply of personal protective equipment (PPE) is inadequate throughout the United States and the world. This is especially true of N95 respirators. The cost of PPE is high. There are numerous cases of providers working […]
• BCG Against SARS-CoV-2: Second Youth of an Old Age Vaccine?6th August 2020
  The sudden outbreak of the COVID-19 pandemic, caused by SARS-CoV-2, has put the whole world into a difficult situation, asking for the immediate development of therapeutics and vaccines against the disease. Bacillus Calmette-Guérin (BCG), an […]
• Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2.6th August 2020
  The spread of new coronavirus infection starting December 2019 as novel SARS-CoV-2, identified as the causing agent of COVID-19, has affected all over the world and been declared as pandemic. Approximately, more than 8,807,398 confirmed […]
• Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2.6th August 2020
  The spike protein S of SARS coronavirus 2 (SARS-CoV-2) binds ACE2 on host cells to initiate entry, and soluble ACE2 is a therapeutic candidate that neutralizes infection by acting as a decoy. Using deep mutagenesis, […]
• Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients.6th August 2020
  The SARS-CoV-2 spike (S) protein, the viral mediator for binding and entry into the host cell, has sparked great interest as a target for vaccine development and treatments with neutralizing antibodies. Initial data suggest that […]
• Dying ‘due to’ or ‘with’ COVID-19: a cause of death analysis in hospitalised patients.6th August 2020
  The SARS-CoV-2 pandemic is accompanied by an ever-rising death toll attributed to coronavirus disease 2019 (COVID-19), but questions have persisted regarding deaths formally attributed to COVID-19. We aimed to provide an independent review of clinical […]
• Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein.6th August 2020
  The recent outbreak of novel coronavirus (SARS-CoV-2 or 2019-nCoV) and its worldwide spread is posing one of the major threats to human health and the world economy. It has been suggested that SARS-CoV-2 is similar […]
• Molecular docking, molecular dynamics simulations and reactivity, studies on approved drugs library targeting ACE2 and SARS-CoV-2 binding with ACE2.6th August 2020
  The recent new contagion coronavirus 2019 (COVID-19) disease is a new generation of severe acute respiratory syndrome coronavirus-2 SARS-CoV-2 which infected millions confirmed cases and hundreds of thousands death cases around the world so far. […]
• Thyroid cancer in the Era of COVID-19.6th August 2020
  The recent coronavirus infectious disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is placing health systems in serious challenges worldwide. Shocking statistics each day has prompted the World Health Organization to officially […]
• Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach.6th August 2020
  The rapidly spreading, highly contagious and pathogenic SARS-coronavirus 2 (SARS-CoV-2) associated Coronavirus Disease 2019 (COVID-19) has been declared as a pandemic by the World Health Organization (WHO). The novel 2019 SARS-CoV-2 enters the host cell […]
• Psychological Distress Amongst Health Workers and the General Public During the COVID-19 Pandemic in Saudi Arabia.6th August 2020
  The rapid spread of COVID-19 worldwide has confined millions of people to their homes and has caused a substantial degree of psychological distress. This study aims to investigate the psychological distress impact of the COVID-19 […]
• Performance of Radiologists in the Evaluation of the Chest Radiography with the Use of a “new software score” in Coronavirus Disease 2019 Pneumonia Suspected Patients.6th August 2020
  The purpose of this study is to assess the performance of radiologists using a new software called “COVID-19 score” when performing chest radiography on patients potentially infected by coronavirus disease 2019 (COVID-19) pneumonia. Chest radiography […]
• Dynamical evolution of COVID-19 in Italy with an evaluation of the size of the asymptomatic infective population.6th August 2020
  The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of […]
• The Impact of COVID-19 Crisis upon the Consumer Buying Behavior of Fresh Vegetables Directly from Local Producers. Case Study: The Quarantined Area of Suceava County, Romania.6th August 2020
  The present paper intends to address the impact of COVID-19 crisis upon the consumer buying behavior of fresh vegetables directly from local producers as observed 30 days later, after enforcing the state of emergency in […]
• Seasonality of Coronavirus 229E, HKU1, NL63, and OC43 From 2014 to 2020.6th August 2020
  The possibility of seasonality of COVID-19 is being discussed; we show clinical microbiology laboratory data illustrating seasonality of coronaviruses 229E, HKU1, NL63, and OC43. The data shown are specific to the 4 studied coronaviruses and […]
• Point-of-care testing: place of France in the world National survey in healthcare establisments in 2019.6th August 2020
  The point-of-care tests (POCT) are subject to accreditation. A national inventory survey provides a synthesis of knowledge. The survey distributed 31 questions in 2019. 147 responses were received (75% biologists, 49% CHU, 42% CHG). Only […]
• Does the physician in triage strategy improve door-to-balloon time for patients with STEMI?6th August 2020
  The physician in triage (PIT) strategy was implemented in the emergency department (ED) of the Soroka University Medical Center (SUMC) to improve overcrowding and waiting time. Our objective in the current study was to assess […]
• Covid-19 Infection in Older Adults: A Geriatrician’s Perspective.6th August 2020
  The pandemic of the Covid-19 virus has become the main issue all over the world. In its current form, the disease is more severe in geriatric cases and individuals with chronic disease, even causing death. […]
• Effects of COVID-19 Pandemic on Health and Wellbeing of Older People: A Comprehensive Review.6th August 2020
  The pandemic is unavoidable; in addition to increased morbidity and mortality, they profoundly affect people and economies at every level. The negative effects of pandemics are more severe in marginalized populations such as older adults […]
• SARS-CoV-2 RNA Dependent RNA polymerase (RdRp) – A drug repurposing study.6th August 2020
  The outbreak of SARS-CoV-2 in December 2019 in China subsequently lead to a pandemic. Lack of vaccine and specific anti-viral drugs started a global health disaster. For a sustained control and protection, development of potential […]
• Face Masks and Respirators in the Fight against the COVID-19 Pandemic: A Review of Current Materials, Advances and Future Perspectives.6th August 2020
  The outbreak of COVID-19 has spread rapidly across the globe, greatly affecting how humans as a whole interact, work and go about their daily life. One of the key pieces of personal protective equipment (PPE) […]
• Forecasting the daily and cumulative number of cases for the COVID-19 pandemic in India.6th August 2020
  The ongoing novel coronavirus epidemic was announced a pandemic by the World Health Organization on March 11, 2020, and the Government of India declared a nationwide lockdown on March 25, 2020 to prevent community transmission […]
• Symptoms of Posttraumatic Stress, Anxiety, Depression, Levels of Resilience and Burnout in Spanish Health Personnel during the COVID-19 Pandemic.6th August 2020
  The number of health workers infected with COVID-19 in Spain is one of the highest in the world. The aim of this study is to analyse posttraumatic stress, anxiety and depression during the COVID-19 pandemic. […]
• When Second Best Might Be the Best: Using Hospitalization Data to Monitor the Novel Coronavirus Pandemic.6th August 2020
  The novel coronavirus’ high rate of asymptomatic transmission combined with a lack of testing kits call for a different approach to monitor its spread and severity. We proposed the use of hospitalizations and hospital utilization […]
• Hypercoagulable State in COVID-19: A Case Series of Three Patients.6th August 2020
  The novel coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that originated in China in late 2019, has caused significant morbidity and mortality worldwide. Although fever, cough, and shortness of […]
• Public Trust and Compliance with the Precautionary Measures Against COVID-19 Employed by Authorities in Saudi Arabia.6th August 2020
  The newly emerged and highly infectious coronavirus disease (COVID-19), which first broke out in Wuhan, China, has invaded most countries around the globe. As both the daily positive cases and death toll increase, countries have […]
• Preventive and treatment strategies of COVID-19: From community to clinical trials.6th August 2020
  The latest threat to global health is the form of the ongoing Coronavirus Disease 2019 (COVID-19) pandemic. This new coronavirus (SARS-COV-2) started as a local outbreak in Wuhan, China but soon tightened its grip on […]
• Determining the true burden of kidney stone disease.6th August 2020
  The incidence and prevalence of kidney stones have increased over the past four decades. However, the diagnosis of ‘kidney stone’ can range from an incidental asymptomatic finding of limited clinical significance to multiple painful episodes […]
• How Patients With Chronic Liver Diseases Succeed to Deal With COVID-19?6th August 2020
  The human pathogenic coronaviruses cause infections of the respiratory tract from mild to severe ranges. Mild cases may look like the common cold, while cases with severe disease may represent severe acute respiratory syndrome (SARS), […]
• Identification of very low-risk acute chest pain patients without troponin testing.6th August 2020
  The HEART Pathway combines a History ECG Age Risk factor (HEAR) score and serial troponins to risk stratify patients with acute chest pain. However, it is unclear whether patients with HEAR scores of <1 require […]
• Association of Comorbidities With Pneumonia and Death Among COVID-19 Patients in Mexico: A Nationwide Cross-sectional Study.6th August 2020
  The goal of this study was to identify chronic conditions and multimorbidity patterns in patients with coronavirus disease 2019 (COVID-19) and to examine their associations with pneumonia and death.This cross-sectional study analyzed the official data […]
• SARS-CoV-2 Infection and COVID-19 During Pregnancy: A Multidisciplinary Review.6th August 2020
  The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has been associated with worse outcomes in several patient populations, including the elderly and those with chronic […]

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