The Latest Clinical Research Articles from Leading Medical Journals
A selection of the latest clinical research articles from leading peer-reviewed medical journals. You can tailor the feed by selecting your specialty / sub-specialty in the menu above. Or browse by medical conditions, drugs and clinical guidelines.
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- Willingness to receive SARS-CoV-2 vaccine among healthcare workers in public institutions of Zhejiang Province, China.This study aims to investigate healthcare workers’ (HCWs) willingness to receive SARS-CoV-2 vaccine in Zhejiang and to discover the related influential factors. The survey was conducted in six regions of Zhejiang Province, China, and 13 hospitals and 12 Centers for Disease Control […]
- Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials?The COVID-19 has become of striking interest since the number of deaths is constantly rising all over the globe, and the search for an efficient treatment is more urgent. In light of this worrisome scenario, this opinion review aimed to discuss the […]
- Whole exome sequencing analysis identifies novel Stargardt disease-related gene mutations in Chinese Stargardt disease and retinitis pigmentosa patients.To delineate the disease-causing mutations of the Stargardt disease-related genes in Chinese patients diagnosed with Stargardt disease or retinitis pigmentosa (RP) by whole exome sequencing analysis.A total of 123 sporadic RP or Stargardt disease patients and 2 Stargardt disease families were recruited. […]
- When politics collides with public health: COVID-19 vaccine country of origin and vaccination acceptance in Brazil.This study examines the effect of the country of origin of the vaccine on vaccination acceptance against COVID-19. More specifically, we show how the political context in Brazil has affected acceptance of vaccines produced in China, Russia, the US, and England at […]
- When lockdown policies amplify social inequalities in COVID-19 infections: evidence from a cross-sectional population-based survey in France.Significant differences in COVID-19 incidence by gender, class and race/ethnicity are recorded in many countries in the world. Lockdown measures, shown to be effective in reducing the number of new cases, may not have been effective in the same way for all, […]
- Visual scoring of chest CT at hospital admission predicts hospitalization time and intensive care admission in Covid-19.Chest CT is prognostic in Covid-19 but there is a lack of consensus on how to report the CT findings. A chest CT scoring system, ÖCoS, was implemented in clinical routine on 1 April 2020, in Örebro Region, Sweden. The ÖCoS-severity score […]
- Ventilation management in acute respiratory failure related to COVID-19 versus ARDS from another origin – a descriptive narrative review.It is uncertain whether ventilation in patients with acute respiratory failure related to coronavirus disease 2019 (COVID-19) differs from that in patients with acute respiratory distress syndrome (ARDS) from another origin.We undertook two literature searches in PubMed to identify observational studies reporting […]
- Venous Leg Ulcers: A Review of Published Assessment and Treatment Algorithms.Significance: Chronic venous disease (CVD) is prevalent in the aging population and leads to venous leg ulcers (VLUs). These wounds can last and recur for years, significantly impacting quality of life. A large body of literature exists on CVD and VLU diagnosis […]
- Validity and reliability of the Persian version of the nurse spiritual care therapeutics scale (NSCTS).Dealing with the spiritual needs of patients has been recognized as one of the principles of holistic care in nursing. Therefore, it is necessary for nurses to deal with the spiritual issues of patients. Also, a valid and reliable scale is needed […]
- Vaginal Examinations During Childbirth: Consent, Coercion and COVID-19.In this paper I assess the labour ward admission policies introduced by some National Health Service (NHS) trusts during the COVID-19 pandemic, arguing that these intersected with other policies in a manner which may have coerced birthing people into consenting to vaginal […]
- Vaccine development for emerging infectious diseases.Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of […]
- Urinary Growth Differentiation Factor-15 (GDF15) levels as a biomarker of adverse outcomes and biopsy findings in chronic kidney disease.Growth Differentiation Factor-15 (GDF15) is a member of the TGF-β superfamily. Increased serum GDF15 has been associated with increased risk of chronic kidney disease (CKD) progression. However, no prior studies have addressed the significance of urinary GDF15 in adult CKD.We measured serum […]
- Unilateral clubbing-like digital thickening as a clinical manifestation of low-flow vascular malformations: a series of 13 cases.Digital clubbing is a well-known clinical sign characterized by thickening of the distal phalanges of the fingers and toes. Unilateral clubbing occurs less frequently. A previous report showed for the first time two cases of unilateral clubbing as a clinical manifestation of […]
- Unexpected decline in pediatric asthma morbidity during the coronavirus pandemic.The Coronavirus disease 2019 (COVID-19) pandemic profoundly impacted health care utilization. We evaluated asthma-related emergency department (ED) and inpatient health care utilization by a county-specific Medicaid population, ages 2-18, during the COVID-19 pandemic and compared it to utilization from a 3-year average […]
- Ultraviolet germicidal irradiation (UVGI) for in-duct airborne bioaerosol disinfection: Review and analysis of design factors.The rapid increase in global cases of COVID-19 illness and death requires the implementation of appropriate and efficient engineering controls to improve indoor air quality. This paper focuses on the use of the ultraviolet germicidal irradiation (UVGI) air purification technology in HVAC […]
- Two Sides of the Coin: Lack of Academic Integrity in Exams During the Corona Pandemic, Students’ and Lecturers’ Perceptions.The Covid-19 pandemic that entered our lives suddenly in 2020 compelled higher education systems throughout the world to transfer to online learning, including online evaluation. A severe problem of online evaluation is that it enables various technological possibilities that facilitate students’ unethical […]
- TRB sequences targeting ORF1a/b are associated with disease severity in hospitalized COVID-19 patients.The potential protective or pathogenic role of the adaptive immune response to SARS-CoV-2 infection has been vigorously debated. While COVID-19 patients consistently generate a T lymphocyte response to SARS-CoV-2 antigens, evidence of significant immune dysregulation in these patients continues to accumulate. In […]
- Trauma mechanism and patient reported outcome in tibial plateau fractures with posterior involvement.Posterior tibial plateau fractures (PTPF) have a high impact on functional outcome and the optimal treatment strategy is not well established. The goal of this study was to assess the relationship between trauma mechanism, fracture morphology and functional outcome in a large […]
- Transcanal Endoscopic Retrograde Mastoidectomy for Cholesteatoma: A Prospective Study.To evaluate the feasibility, morphological, and functional outcomes of endoscopic retrograde transcanal mastoidectomy.Prospective study.Tertiary Referral Hospital.We analyzed 31 patients with a diagnosis of chronic otitis media with cholesteatoma that extended to the mastoid cavity who underwent endoscopic transcanal retrograde canal wall down […]
- Towards ‘automated gonioscopy’: a deep learning algorithm for 360° angle assessment by swept-source optical coherence tomography.To validate a deep learning (DL) algorithm (DLA) for 360° angle assessment on swept-source optical coherence tomography (SS-OCT) (CASIA SS-1000, Tomey Corporation, Nagoya, Japan).This was a reliability analysis from a cross-sectional study. An independent test set of 39 936 SS-OCT scans from […]